Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

343 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Cholesterol elevation impairs glucose-stimulated Ca(2+) signaling in mouse pancreatic β-cells.
Lee AK, Yeung-Yam-Wah V, Tse FW, Tse A. Lee AK, et al. Endocrinology. 2011 Sep;152(9):3351-61. doi: 10.1210/en.2011-0124. Epub 2011 Jun 28. Endocrinology. 2011. PMID: 21712366
When cholesterol-enriched β-cells were challenged with tolbutamide, there was a decrease in the amplitude of the Ca(2+) signal, and it was associated with a reduction in the cell current density of voltage-gated Ca(2+) channels (VGCC). ...Thus, cholesterol enrichmen …
When cholesterol-enriched β-cells were challenged with tolbutamide, there was a decrease in the amplitude of the Ca(2+) signal, and i …
Arginine Vasopressin Potentiates the Stimulatory Action of CRH on Pituitary Corticotropes via a Protein Kinase C-Dependent Reduction of the Background TREK-1 Current.
Lee AK, Tse FW, Tse A. Lee AK, et al. Endocrinology. 2015 Oct;156(10):3661-72. doi: 10.1210/en.2015-1293. Epub 2015 Aug 6. Endocrinology. 2015. PMID: 26248219
Using the perforated patch-clamp technique to monitor membrane potentials in mouse corticotropes, we found that AVP triggered a transient hyperpolarization that was followed by a sustained depolarization. ...In cells with minimal perturbation of [Ca(2+)]i and backgr …
Using the perforated patch-clamp technique to monitor membrane potentials in mouse corticotropes, we found that AVP triggered a trans …
Autocrine and paracrine actions of ATP in rat carotid body.
Tse A, Yan L, Lee AK, Tse FW. Tse A, et al. Can J Physiol Pharmacol. 2012 Jun;90(6):705-11. doi: 10.1139/y2012-054. Epub 2012 Apr 17. Can J Physiol Pharmacol. 2012. PMID: 22509744 Review.
In contrast, adenosine (an ATP metabolite) triggers depolarization and [Ca(2+)](i) rise in glomus cells via A(2A) receptors. ...Such mechanisms may allow cyclic release of transmitters from glomus cells during prolonged hypoxia without causing cellular damage from a
In contrast, adenosine (an ATP metabolite) triggers depolarization and [Ca(2+)](i) rise in glomus cells via A(2A) receptors. ...Such …
Granule matrix property and rapid "kiss-and-run" exocytosis contribute to the different kinetics of catecholamine release from carotid glomus and adrenal chromaffin cells at matched quantal size.
Wang N, Lee AK, Yan L, Simpson MR, Tse A, Tse FW. Wang N, et al. Can J Physiol Pharmacol. 2012 Jun;90(6):791-801. doi: 10.1139/y2012-040. Epub 2012 Apr 17. Can J Physiol Pharmacol. 2012. PMID: 22506963
Yet, at the same range of quantal size (Q, the total amount of catecholamine that can be released from a granule), the kinetics of every phase of the amperometric spike signals from glomus cells was faster. Our data indicate that the last phenomenon involved at least 2 mec …
Yet, at the same range of quantal size (Q, the total amount of catecholamine that can be released from a granule), the kinetics of ev …
Ca2+ homeostasis and exocytosis in carotid glomus cells: role of mitochondria.
Yan L, Lee AK, Tse FW, Tse A. Yan L, et al. Cell Calcium. 2012 Feb;51(2):155-63. doi: 10.1016/j.ceca.2011.12.003. Epub 2011 Dec 29. Cell Calcium. 2012. PMID: 22209034
Under whole-cell voltage clamp conditions, application of the mitochondrial inhibitors, carbonyl cyanide m-chlorophenylhydrazone (CCCP) or cyanide caused a dramatic slowing in the decay of the depolarization-triggered Ca(2+) signal in glomus cells. ...Hypoxia also slowed c …
Under whole-cell voltage clamp conditions, application of the mitochondrial inhibitors, carbonyl cyanide m-chlorophenylhydrazone (CCCP) or c …
Arachidonic acid mobilizes Ca2+ from the endoplasmic reticulum and an acidic store in rat pancreatic β cells.
Yeung-Yam-Wah V, Lee AK, Tse A. Yeung-Yam-Wah V, et al. Cell Calcium. 2012 Feb;51(2):140-8. doi: 10.1016/j.ceca.2011.11.012. Epub 2011 Dec 22. Cell Calcium. 2012. PMID: 22197025
In contrast, stimulation of IP(3) receptors via intracellular dialysis of adenophostin A, or exogenous application of ATP largely abolished the AA-mediated Ca(2+) signal. ...
In contrast, stimulation of IP(3) receptors via intracellular dialysis of adenophostin A, or exogenous application of ATP largely abo …
Reciprocal regulation of TREK-1 channels by arachidonic acid and CRH in mouse corticotropes.
Lee AK, Smart JL, Rubinstein M, Low MJ, Tse A. Lee AK, et al. Endocrinology. 2011 May;152(5):1901-10. doi: 10.1210/en.2010-1066. Epub 2011 Feb 22. Endocrinology. 2011. PMID: 21343252 Free PMC article.
Using the patch clamp technique, we examined the action of AA on the excitability of single pituitary corticotropes obtained from a transgenic mouse strain that expresses the enhanced green fluorescent protein driven by the proopiomelanocortin promoter. ...Under voltage cl …
Using the patch clamp technique, we examined the action of AA on the excitability of single pituitary corticotropes obtained from a t …
Influence of cholesterol on catecholamine release from the fusion pore of large dense core chromaffin granules.
Wang N, Kwan C, Gong X, de Chaves EP, Tse A, Tse FW. Wang N, et al. J Neurosci. 2010 Mar 17;30(11):3904-11. doi: 10.1523/JNEUROSCI.4000-09.2010. J Neurosci. 2010. PMID: 20237261 Free PMC article.
In contrast, the reduction of cellular cholesterol shortened the "prespike foot" signals (which reflect the leakage of catecholamine via a semi-stable fusion pore) and reduced the proportion of "stand-alone foot" signals (which reflect the release via a flickering f …
In contrast, the reduction of cellular cholesterol shortened the "prespike foot" signals (which reflect the leakage of catecholamine via …
Arachidonic acid stimulates extracellular Ca(2+) entry in rat pancreatic beta cells via activation of the noncapacitative arachidonate-regulated Ca(2+) (ARC) channels.
Yeung-Yam-Wah V, Lee AK, Tse FW, Tse A. Yeung-Yam-Wah V, et al. Cell Calcium. 2010 Jan;47(1):77-83. doi: 10.1016/j.ceca.2009.11.007. Epub 2009 Dec 16. Cell Calcium. 2010. PMID: 20018371
We investigated whether AA activated extracellular Ca(2+) entry in rat pancreatic beta cells via a pathway that was independent of the activation of voltage-gated Ca(2+) channels. ...Consistent with this, intracellular application of the charged membrane-impermeant analog …
We investigated whether AA activated extracellular Ca(2+) entry in rat pancreatic beta cells via a pathway that was independent of th …
Stimulatory actions of pituitary adenylate cyclase-activating polypeptide (PACAP) in rat carotid glomus cells.
Xu F, Tse FW, Tse A. Xu F, et al. Adv Exp Med Biol. 2008;605:69-74. doi: 10.1007/978-0-387-73693-8_12. Adv Exp Med Biol. 2008. PMID: 18085249
We suggest that the inhibition of a TEA-insensitive current is a mechanism underlying the PACAP-mediated [Ca2+]i rise in glomus cells. ...
We suggest that the inhibition of a TEA-insensitive current is a mechanism underlying the PACAP-mediated [Ca2+]i rise in glomu …
343 results
Jump to page
Feedback