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TAM receptors in apoptotic cell clearance, autoimmunity, and cancer.
Nguyen KQ, Tsou WI, Kotenko S, Birge RB. Nguyen KQ, et al. Among authors: tsou wi. Autoimmunity. 2013 Aug;46(5):294-7. doi: 10.3109/08916934.2013.794515. Epub 2013 May 10. Autoimmunity. 2013. PMID: 23662598 Review.
Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression.
Kasikara C, Kumar S, Kimani S, Tsou WI, Geng K, Davra V, Sriram G, Devoe C, Nguyen KN, Antes A, Krantz A, Rymarczyk G, Wilczynski A, Empig C, Freimark B, Gray M, Schlunegger K, Hutchins J, Kotenko SV, Birge RB. Kasikara C, et al. Among authors: tsou wi. Mol Cancer Res. 2017 Jun;15(6):753-764. doi: 10.1158/1541-7786.MCR-16-0350. Epub 2017 Feb 9. Mol Cancer Res. 2017. PMID: 28184013 Free article.
Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase.
Kimani SG, Kumar S, Davra V, Chang YJ, Kasikara C, Geng K, Tsou WI, Wang S, Hoque M, Boháč A, Lewis-Antes A, De Lorenzo MS, Kotenko SV, Birge RB. Kimani SG, et al. Among authors: tsou wi. Cell Commun Signal. 2016 Sep 6;14(1):19. doi: 10.1186/s12964-016-0142-1. Cell Commun Signal. 2016. PMID: 27595981 Free PMC article.
Overexpression of MERTK receptor tyrosine kinase in epithelial cancer cells drives efferocytosis in a gain-of-function capacity.
Nguyen KQ, Tsou WI, Calarese DA, Kimani SG, Singh S, Hsieh S, Liu Y, Lu B, Wu Y, Garforth SJ, Almo SC, Kotenko SV, Birge RB. Nguyen KQ, et al. Among authors: tsou wi. J Biol Chem. 2014 Sep 12;289(37):25737-49. doi: 10.1074/jbc.M114.570838. Epub 2014 Jul 29. J Biol Chem. 2014. PMID: 25074939 Free PMC article.
Receptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activation.
Tsou WI, Nguyen KQ, Calarese DA, Garforth SJ, Antes AL, Smirnov SV, Almo SC, Birge RB, Kotenko SV. Tsou WI, et al. J Biol Chem. 2014 Sep 12;289(37):25750-63. doi: 10.1074/jbc.M114.569020. Epub 2014 Jul 29. J Biol Chem. 2014. PMID: 25074926 Free PMC article.
Paxillin phosphorylation by JNK and p38 is required for NFAT activation.
Lee YC, Chang AY, Lin-Feng MH, Tsou WI, Chiang IH, Lai MZ. Lee YC, et al. Among authors: tsou wi. Eur J Immunol. 2012 Aug;42(8):2165-75. doi: 10.1002/eji.201142192. Eur J Immunol. 2012. PMID: 22865050 Free article.
Reactive oxygen species promote raft formation in T lymphocytes.
Lu SP, Lin Feng MH, Huang HL, Huang YC, Tsou WI, Lai MZ. Lu SP, et al. Among authors: tsou wi. Free Radic Biol Med. 2007 Apr 1;42(7):936-44. doi: 10.1016/j.freeradbiomed.2006.11.027. Epub 2006 Dec 2. Free Radic Biol Med. 2007. PMID: 17349922
Notch inhibits apoptosis by direct interference with XIAP ubiquitination and degradation.
Liu WH, Hsiao HW, Tsou WI, Lai MZ. Liu WH, et al. Among authors: tsou wi. EMBO J. 2007 Mar 21;26(6):1660-9. doi: 10.1038/sj.emboj.7601611. Epub 2007 Feb 22. EMBO J. 2007. PMID: 17318174 Free PMC article.