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Inhibition of γ-glutamyltransferase ameliorates ischaemia-reoxygenation tissue damage in rats with hepatic steatosis.
Kubota R, Hayashi N, Kinoshita K, Saito T, Ozaki K, Ueda Y, Tsuchishima M, Tsutsumi M, George J. Kubota R, et al. Among authors: tsuchishima m. Br J Pharmacol. 2020 Sep 10;177(22):5195-207. doi: 10.1111/bph.15258. Online ahead of print. Br J Pharmacol. 2020. PMID: 32910829
Metabolism of N-nitrosodimethylamine, methylation of macromolecules, and development of hepatic fibrosis in rodent models.
George J, Tsuchishima M, Tsutsumi M. George J, et al. Among authors: tsuchishima m. J Mol Med (Berl). 2020 Sep;98(9):1203-1213. doi: 10.1007/s00109-020-01950-7. Epub 2020 Jul 14. J Mol Med (Berl). 2020. PMID: 32666246 Review.
The combination of fatty liver and increased gamma-glutamyl transpeptidase levels as a risk factor for atherosclerotic plaque development in apparently healthy people.
Kinoshita K, Toshikuni N, Saito T, Hayashi N, Minato T, Matsue Y, Ueda Y, Tsuchishima M, Tsutsumi M. Kinoshita K, et al. Among authors: tsuchishima m. Turk J Med Sci. 2019 Oct 24;49(5):1350-1357. doi: 10.3906/sag-1901-166. Turk J Med Sci. 2019. PMID: 31648507 Free PMC article.
Recombinant thrombomodulin prevented hepatic ischemia-reperfusion injury by inhibiting high-mobility group box 1 in rats.
Hirakawa Y, Tsuchishima M, Fukumura A, Kinoshita K, Hayashi N, Saito T, George J, Toshikuni N, Ueda Y, Tsutsumi M. Hirakawa Y, et al. Among authors: tsuchishima m. Eur J Pharmacol. 2019 Nov 15;863:172681. doi: 10.1016/j.ejphar.2019.172681. Epub 2019 Sep 19. Eur J Pharmacol. 2019. PMID: 31542482
Alteration of Trace Elements during Pathogenesis of N-Nitrosodimethylamine Induced Hepatic Fibrosis.
George J, Tsutsumi M, Tsuchishima M. George J, et al. Among authors: tsuchishima m. Sci Rep. 2019 Jan 24;9(1):708. doi: 10.1038/s41598-018-37516-4. Sci Rep. 2019. PMID: 30679730 Free PMC article.
Molecular mechanisms in the pathogenesis of N-nitrosodimethylamine induced hepatic fibrosis.
George J, Tsuchishima M, Tsutsumi M. George J, et al. Among authors: tsuchishima m. Cell Death Dis. 2019 Jan 8;10(1):18. doi: 10.1038/s41419-018-1272-8. Cell Death Dis. 2019. PMID: 30622238 Free PMC article. Review.
An Image Fusion System for Estimating the Therapeutic Effects of Radiofrequency Ablation on Hepatocellular Carcinoma.
Toshikuni N, Matsue Y, Ozaki K, Yamada K, Hayashi N, Tsuchishima M, Tsutsumi M. Toshikuni N, et al. Among authors: tsuchishima m. Radiol Oncol. 2017 Jul 18;51(3):263-269. doi: 10.1515/raon-2017-0028. eCollection 2017 Sep. Radiol Oncol. 2017. PMID: 28959162 Free PMC article.
Associations of Fatty Liver Disease with Hypertension, Diabetes, and Dyslipidemia: Comparison between Alcoholic and Nonalcoholic Steatohepatitis.
Toshikuni N, Tsuchishima M, Fukumura A, Arisawa T, Tsutsumi M. Toshikuni N, et al. Among authors: tsuchishima m. Gastroenterol Res Pract. 2017;2017:9127847. doi: 10.1155/2017/9127847. Epub 2017 Aug 22. Gastroenterol Res Pract. 2017. PMID: 28912806 Free PMC article.
MMP-13 deletion decreases profibrogenic molecules and attenuates N-nitrosodimethylamine-induced liver injury and fibrosis in mice.
George J, Tsutsumi M, Tsuchishima M. George J, et al. Among authors: tsuchishima m. J Cell Mol Med. 2017 Dec;21(12):3821-3835. doi: 10.1111/jcmm.13304. Epub 2017 Aug 7. J Cell Mol Med. 2017. PMID: 28782260 Free PMC article.
GGsTop, a novel and specific γ-glutamyl transpeptidase inhibitor, protects hepatic ischemia-reperfusion injury in rats.
Tamura K, Hayashi N, George J, Toshikuni N, Arisawa T, Hiratake J, Tsuchishima M, Tsutsumi M. Tamura K, et al. Among authors: tsuchishima m. Am J Physiol Gastrointest Liver Physiol. 2016 Aug 1;311(2):G305-12. doi: 10.1152/ajpgi.00439.2015. Epub 2016 Jun 30. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27365338 Free article.
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