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Isolation, characterization and biological activities of novel triprenyl phenols as pancreatic cholesterol esterase inhibitors produced by Stachybotrys sp. F-1839.
Sakai K, Watanabe K, Masuda K, Tsuji M, Hasumi K, Endo A. Sakai K, et al. Among authors: Tsuji M. J Antibiot (Tokyo). 1995 Jun;48(6):447-56. doi: 10.7164/antibiotics.48.447. J Antibiot (Tokyo). 1995. PMID: 7622428
These compounds inhibited pancreatic cholesterol esterase by 50% at 6 x 10(-5) to 1.1 x 10(-1) M. Inhibition of the enzyme by compound 2, the most potent one among these compounds, was time-dependent and irreversible. ...
These compounds inhibited pancreatic cholesterol esterase by 50% at 6 x 10(-5) to 1.1 x 10(-1) M. Inhibition of the enzyme by compoun …
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