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Cell death regulation by the Bcl-2 protein family in the mitochondria.
Tsujimoto Y. Tsujimoto Y. J Cell Physiol. 2003 May;195(2):158-67. doi: 10.1002/jcp.10254. J Cell Physiol. 2003. PMID: 12652643 Review.
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G. Galluzzi L, et al. Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Cell Death Differ. 2018. PMID: 29362479 Free PMC article. Review.
Inhibition of epithelial cell death by Bcl-2 improved chronic colitis in IL-10 KO mice.
Mizushima T, Arakawa S, Sanada Y, Yoshino I, Miyazaki D, Urushima H, Tsujimoto Y, Ito T, Shimizu S. Mizushima T, et al. Am J Pathol. 2013 Dec;183(6):1936-1944. doi: 10.1016/j.ajpath.2013.08.012. Am J Pathol. 2013. PMID: 24266926
Screening of cell death genes with a mammalian genome-wide RNAi library.
Tsujii H, Eguchi Y, Chenchik A, Mizutani T, Yamada K, Tsujimoto Y. Tsujii H, et al. J Biochem. 2010 Aug;148(2):157-70. doi: 10.1093/jb/mvq042. Epub 2010 Apr 26. J Biochem. 2010. PMID: 20421362
Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice.
Hikita H, Takehara T, Kodama T, Shimizu S, Shigekawa M, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Shimizu S, Tsujimoto Y, Hayashi N. Hikita H, et al. Hepatology. 2011 Jul;54(1):240-51. doi: 10.1002/hep.24305. Epub 2011 Apr 11. Hepatology. 2011. PMID: 21425311
Bcl2 deficiency activates FoxO through Akt inactivation and accelerates osteoblast differentiation.
Moriishi T, Kawai Y, Komori H, Rokutanda S, Eguchi Y, Tsujimoto Y, Asahina I, Komori T. Moriishi T, et al. PLoS One. 2014 Jan 20;9(1):e86629. doi: 10.1371/journal.pone.0086629. eCollection 2014. PLoS One. 2014. PMID: 24466179 Free PMC article.
Bcl2 enhances survival of newborn neurons in the normal and ischemic hippocampus.
Sasaki T, Kitagawa K, Yagita Y, Sugiura S, Omura-Matsuoka E, Tanaka S, Matsushita K, Okano H, Tsujimoto Y, Hori M. Sasaki T, et al. J Neurosci Res. 2006 Nov 1;84(6):1187-96. doi: 10.1002/jnr.21036. J Neurosci Res. 2006. PMID: 16941650
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