Peroxisome proliferator-activated receptor gamma suppresses proximal alpha1(I) collagen promoter via inhibition of p300-facilitated NF-I binding to DNA in hepatic stellate cells.
Yavrom S, Chen L, Xiong S, Wang J, Rippe RA, Tsukamoto H.
Yavrom S, et al. Among authors: tsukamoto h.
J Biol Chem. 2005 Dec 9;280(49):40650-9. doi: 10.1074/jbc.M510094200. Epub 2005 Oct 10.
J Biol Chem. 2005.
PMID: 16216869
Free article.
Depletion of peroxisome proliferator-activated receptor gamma (PPARgamma) represents one of the key molecular changes that underlie transdifferentiation (activation) of hepatic stellate cells in the genesis of liver fibrosis (Miyahara, T., Schrum, L., Rippe, R., Xiong, S., Yee, …
Depletion of peroxisome proliferator-activated receptor gamma (PPARgamma) represents one of the key molecular changes that underlie transdif …