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10-formyltetrahydrofolate dehydrogenase requires a 4'-phosphopantetheine prosthetic group for catalysis.
Donato H, Krupenko NI, Tsybovsky Y, Krupenko SA. Donato H, et al. Among authors: tsybovsky y. J Biol Chem. 2007 Nov 23;282(47):34159-66. doi: 10.1074/jbc.M707627200. Epub 2007 Sep 20. J Biol Chem. 2007. PMID: 17884809
The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1.
Tsybovsky Y, Malakhau Y, Strickland KC, Krupenko SA. Tsybovsky Y, et al. Chem Biol Interact. 2013 Feb 25;202(1-3):62-9. doi: 10.1016/j.cbi.2012.12.015. Epub 2013 Jan 5. Chem Biol Interact. 2013. PMID: 23295222 Free PMC article.
Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
Tsybovsky Y, Krupenko SA. Tsybovsky Y, et al. J Biol Chem. 2011 Jul 1;286(26):23357-67. doi: 10.1074/jbc.M111.221069. Epub 2011 May 3. J Biol Chem. 2011. PMID: 21540484 Free PMC article.
Enzymatic properties of ALDH1L2, a mitochondrial 10-formyltetrahydrofolate dehydrogenase.
Strickland KC, Krupenko NI, Dubard ME, Hu CJ, Tsybovsky Y, Krupenko SA. Strickland KC, et al. Among authors: tsybovsky y. Chem Biol Interact. 2011 May 30;191(1-3):129-36. doi: 10.1016/j.cbi.2011.01.008. Epub 2011 Jan 14. Chem Biol Interact. 2011. PMID: 21238436 Free PMC article.
Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases.
Tsybovsky Y, Donato H, Krupenko NI, Davies C, Krupenko SA. Tsybovsky Y, et al. Biochemistry. 2007 Mar 20;46(11):2917-29. doi: 10.1021/bi0619573. Epub 2007 Feb 16. Biochemistry. 2007. PMID: 17302434
Aldehyde dehydrogenase homologous folate enzymes: Evolutionary switch between cytoplasmic and mitochondrial localization.
Krupenko NI, Holmes RS, Tsybovsky Y, Krupenko SA. Krupenko NI, et al. Among authors: tsybovsky y. Chem Biol Interact. 2015 Jun 5;234:12-7. doi: 10.1016/j.cbi.2014.12.022. Epub 2014 Dec 27. Chem Biol Interact. 2015. PMID: 25549576 Free PMC article.
Structural Insights into the Drosophila melanogaster Retinol Dehydrogenase, a Member of the Short-Chain Dehydrogenase/Reductase Family.
Hofmann L, Tsybovsky Y, Alexander NS, Babino D, Leung NY, Montell C, Banerjee S, von Lintig J, Palczewski K. Hofmann L, et al. Among authors: tsybovsky y. Biochemistry. 2016 Nov 29;55(47):6545-6557. doi: 10.1021/acs.biochem.6b00907. Epub 2016 Nov 16. Biochemistry. 2016. PMID: 27809489 Free PMC article.
Posttranslational modifications of the photoreceptor-specific ABC transporter ABCA4.
Tsybovsky Y, Wang B, Quazi F, Molday RS, Palczewski K. Tsybovsky Y, et al. Biochemistry. 2011 Aug 16;50(32):6855-66. doi: 10.1021/bi200774w. Epub 2011 Jul 8. Biochemistry. 2011. PMID: 21721517 Free PMC article.
The ATP-binding cassette transporter ABCA4: structural and functional properties and role in retinal disease.
Tsybovsky Y, Molday RS, Palczewski K. Tsybovsky Y, et al. Adv Exp Med Biol. 2010;703:105-25. doi: 10.1007/978-1-4419-5635-4_8. Adv Exp Med Biol. 2010. PMID: 20711710 Free PMC article. Review.
Complexes between photoactivated rhodopsin and transducin: progress and questions.
Jastrzebska B, Tsybovsky Y, Palczewski K. Jastrzebska B, et al. Among authors: tsybovsky y. Biochem J. 2010 Apr 28;428(1):1-10. doi: 10.1042/BJ20100270. Biochem J. 2010. PMID: 20423327 Free PMC article. Review.
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