Tucker GT - Search Results

1

The rational selection of drug interaction studies: implications of recent advances in drug metabolism.

Tucker GT. Tucker GT. Int J Clin Pharmacol Ther Toxicol. 1992 Nov;30(11):550-3. Int J Clin Pharmacol Ther Toxicol. 1992. PMID: 1490831 Review. No abstract available.

2

Histamine inhibition of mixed function oxidase activity in rat and human liver microsomes and in the isolated perfused rat liver.

Morris CQ, Tucker GT, Crewe HK, Harlow JR, Woods HF, Lennard MS. Morris CQ, et al. Among authors: tucker gt. Biochem Pharmacol. 1989 Aug 15;38(16):2639-44. doi: 10.1016/0006-2952(89)90549-2. Biochem Pharmacol. 1989. PMID: 2764987

3

Drug metabolism.

Tucker GT. Tucker GT. Br J Anaesth. 1979 Jul;51(7):603-18. doi: 10.1093/bja/51.7.603. Br J Anaesth. 1979. PMID: 399191 Review. No abstract available.

4

A comparison of the ontogeny of enterocytic and hepatic cytochromes P450 3A in the rat.

Johnson TN, Tanner MS, Tucker GT. Johnson TN, et al. Among authors: tucker gt. Biochem Pharmacol. 2000 Dec 1;60(11):1601-10. doi: 10.1016/s0006-2952(00)00485-8. Biochem Pharmacol. 2000. PMID: 11077042

5

Stereoselective 4-hydroxylation of debrisoquine in Nigerians.

Lennard MS, Tucker GT, Woods HF, Iyun AO, Eichelbaum M. Lennard MS, et al. Among authors: tucker gt. Biochem Pharmacol. 1988 Jan 1;37(1):97-8. doi: 10.1016/0006-2952(88)90759-9. Biochem Pharmacol. 1988. PMID: 3337737 No abstract available.

6

Characterization of metronidazole metabolism by human liver microsomes.

Loft S, Otton SV, Lennard MS, Tucker GT, Poulsen HE. Loft S, et al. Among authors: tucker gt. Biochem Pharmacol. 1991 Apr 15;41(8):1127-34. doi: 10.1016/0006-2952(91)90650-t. Biochem Pharmacol. 1991. PMID: 2009091

7

Influence of debrisoquine oxidation phenotype on exercise tolerance and subjective fatigue after metoprolol and atenolol in healthy subjects.

Lewis RV, Ramsay LE, Jackson PR, Yeo WW, Lennard MS, Tucker GT. Lewis RV, et al. Among authors: tucker gt. Br J Clin Pharmacol. 1991 Apr;31(4):391-8. doi: 10.1111/j.1365-2125.1991.tb05551.x. Br J Clin Pharmacol. 1991. PMID: 2049246 Free PMC article. Clinical Trial.

8

Prediction of in vivo drug clearance from in vitro data. I: impact of inter-individual variability.

Howgate EM, Rowland Yeo K, Proctor NJ, Tucker GT, Rostami-Hodjegan A. Howgate EM, et al. Among authors: tucker gt. Xenobiotica. 2006 Jun;36(6):473-97. doi: 10.1080/00498250600683197. Xenobiotica. 2006. PMID: 16769646

9

Prediction of metabolic drug clearance in humans: in vitro-in vivo extrapolation vs allometric scaling.

Shiran MR, Proctor NJ, Howgate EM, Rowland-Yeo K, Tucker GT, Rostami-Hodjegan A. Shiran MR, et al. Among authors: tucker gt. Xenobiotica. 2006 Jul;36(7):567-80. doi: 10.1080/00498250600761662. Xenobiotica. 2006. PMID: 16864504

10

The demethylenation of methylenedioxymethamphetamine ("ecstasy") by debrisoquine hydroxylase (CYP2D6).

Tucker GT, Lennard MS, Ellis SW, Woods HF, Cho AK, Lin LY, Hiratsuka A, Schmitz DA, Chu TY. Tucker GT, et al. Biochem Pharmacol. 1994 Mar 29;47(7):1151-6. doi: 10.1016/0006-2952(94)90386-7. Biochem Pharmacol. 1994. PMID: 7909223

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