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285 results
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A semi-mechanistic model to predict the effects of liver cirrhosis on drug clearance.
Johnson TN, Boussery K, Rowland-Yeo K, Tucker GT, Rostami-Hodjegan A. Johnson TN, et al. Among authors: tucker gt. Clin Pharmacokinet. 2010 Mar;49(3):189-206. doi: 10.2165/11318160-000000000-00000. Clin Pharmacokinet. 2010. PMID: 20170207
Direct and indirect measurement of the hepatic extraction ratio of indocyanine green in the rat.
Burns E, Ball CE, Christie JP, Broadhead GD, Tucker GT, Bax ND. Burns E, et al. Among authors: tucker gt. Clin Sci (Lond). 1989 May;76(5):503-8. doi: 10.1042/cs0760503. Clin Sci (Lond). 1989. PMID: 2721117
Ab initio molecular modeling in the study of drug metabolism.
Segall MD, Payne MC, Ellis SW, Tucker GT, Boyes RN. Segall MD, et al. Among authors: tucker gt. Eur J Drug Metab Pharmacokinet. 1997 Oct-Dec;22(4):283-9. doi: 10.1007/BF03190958. Eur J Drug Metab Pharmacokinet. 1997. PMID: 9512922
Erratum to: A Re-evaluation and Validation of Ontogeny Functions for Cytochrome P450 1A2 and 3A4 Based on In Vivo Data.
Salem F, Johnson TN, Abduljalil K, Tucker GT, Rostami-Hodjegan A. Salem F, et al. Among authors: tucker gt. Clin Pharmacokinet. 2015 Jun;54(6):671. doi: 10.1007/s40262-015-0284-0. Clin Pharmacokinet. 2015. PMID: 25968247 No abstract available.
A comparison of the ontogeny of enterocytic and hepatic cytochromes P450 3A in the rat.
Johnson TN, Tanner MS, Tucker GT. Johnson TN, et al. Among authors: tucker gt. Biochem Pharmacol. 2000 Dec 1;60(11):1601-10. doi: 10.1016/s0006-2952(00)00485-8. Biochem Pharmacol. 2000. PMID: 11077042
Modified-release hydrocortisone for circadian therapy: a proof-of-principle study in dexamethasone-suppressed normal volunteers.
Newell-Price J, Whiteman M, Rostami-Hodjegan A, Darzy K, Shalet S, Tucker GT, Ross RJ. Newell-Price J, et al. Among authors: tucker gt. Clin Endocrinol (Oxf). 2008 Jan;68(1):130-5. doi: 10.1111/j.1365-2265.2007.03011.x. Epub 2007 Sep 4. Clin Endocrinol (Oxf). 2008. PMID: 17803699 Clinical Trial.
Circadian hydrocortisone infusions in patients with adrenal insufficiency and congenital adrenal hyperplasia.
Merza Z, Rostami-Hodjegan A, Memmott A, Doane A, Ibbotson V, Newell-Price J, Tucker GT, Ross RJ. Merza Z, et al. Among authors: tucker gt. Clin Endocrinol (Oxf). 2006 Jul;65(1):45-50. doi: 10.1111/j.1365-2265.2006.02544.x. Clin Endocrinol (Oxf). 2006. PMID: 16817818 Clinical Trial.
Prediction of in vivo drug clearance from in vitro data. I: impact of inter-individual variability.
Howgate EM, Rowland Yeo K, Proctor NJ, Tucker GT, Rostami-Hodjegan A. Howgate EM, et al. Among authors: tucker gt. Xenobiotica. 2006 Jun;36(6):473-97. doi: 10.1080/00498250600683197. Xenobiotica. 2006. PMID: 16769646
Prediction of metabolic drug clearance in humans: in vitro-in vivo extrapolation vs allometric scaling.
Shiran MR, Proctor NJ, Howgate EM, Rowland-Yeo K, Tucker GT, Rostami-Hodjegan A. Shiran MR, et al. Among authors: tucker gt. Xenobiotica. 2006 Jul;36(7):567-80. doi: 10.1080/00498250600761662. Xenobiotica. 2006. PMID: 16864504
Disparity in holoprotein/apoprotein ratios of different standards used for immunoquantification of hepatic cytochrome P450 enzymes.
Perrett HF, Barter ZE, Jones BC, Yamazaki H, Tucker GT, Rostami-Hodjegan A. Perrett HF, et al. Among authors: tucker gt. Drug Metab Dispos. 2007 Oct;35(10):1733-6. doi: 10.1124/dmd.107.015743. Epub 2007 Jun 28. Drug Metab Dispos. 2007. PMID: 17600083
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