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Genetic risk for attention-deficit/hyperactivity disorder predicts cognitive decline and development of Alzheimer's disease pathophysiology in cognitively unimpaired older adults.
Leffa DT, Ferrari-Souza JP, Bellaver B, Tissot C, Ferreira PCL, Brum WS, Caye A, Lord J, Proitsi P, Martins-Silva T, Tovo-Rodrigues L, Tudorascu DL, Villemagne VL, Cohen AD, Lopez OL, Klunk WE, Karikari TK, Rosa-Neto P, Zimmer ER, Molina BSG, Rohde LA, Pascoal TA; Alzheimer’s Disease Neuroimaging Initiative. Leffa DT, et al. Among authors: tudorascu dl. Mol Psychiatry. 2023 Mar;28(3):1248-1255. doi: 10.1038/s41380-022-01867-2. Epub 2022 Dec 8. Mol Psychiatry. 2023. PMID: 36476732
Potential Utility of Plasma P-Tau and Neurofilament Light Chain as Surrogate Biomarkers for Preventive Clinical Trials.
Ferreira PCL, Ferrari-Souza JP, Tissot C, Bellaver B, Leffa DT, Lussier F, Povala G, Therriault J, Benedet AL, Ashton NJ, Cohen AD, Lopez OL, Tudorascu DL, Klunk WE, Soucy JP, Gauthier S, Villemagne V, Zetterberg H, Blennow K, Rosa-Neto P, Zimmer ER, Karikari TK, Pascoal TA; Alzheimer's Disease Neuroimaging Initiative. Ferreira PCL, et al. Among authors: tudorascu dl. Neurology. 2023 Jul 4;101(1):38-45. doi: 10.1212/WNL.0000000000207115. Epub 2023 Mar 6. Neurology. 2023. PMID: 36878697 Free PMC article.
Plasma p-tau231 and p-tau217 inform on tau tangles aggregation in cognitively impaired individuals.
Ferreira PCL, Therriault J, Tissot C, Ferrari-Souza JP, Benedet AL, Povala G, Bellaver B, Leffa DT, Brum WS, Lussier FZ, Bezgin G, Servaes S, Vermeiren M, Macedo AC, Cabrera A, Stevenson J, Triana-Baltzer G, Kolb H, Rahmouni N, Klunk WE, Lopez OL, Villemagne VL, Cohen A, Tudorascu DL, Zimmer ER, Karikari TK, Ashton NJ, Zetterberg H, Blennow K, Gauthier S, Rosa-Neto P, Pascoal TA. Ferreira PCL, et al. Alzheimers Dement. 2023 Oct;19(10):4463-4474. doi: 10.1002/alz.13393. Epub 2023 Aug 3. Alzheimers Dement. 2023. PMID: 37534889
A guide for researchers seeking training in retrospective data harmonization for population neuroscience studies of Alzheimer's disease and related dementias.
Shaaban CE, Tudorascu DL, Glymour MM, Cohen AD, Thurston RC, Snyder HM, Hohman TJ, Mukherjee S, Yu L, Snitz BE. Shaaban CE, et al. Among authors: tudorascu dl. Front Neuroimaging. 2022;1:978350. doi: 10.3389/fnimg.2022.978350. Epub 2022 Sep 26. Front Neuroimaging. 2022. PMID: 37464990 Free PMC article.
Blood-brain barrier integrity impacts the use of plasma amyloid-β as a proxy of brain amyloid-β pathology.
Bellaver B, Puig-Pijoan A, Ferrari-Souza JP, Leffa DT, Lussier FZ, Ferreira PCL, Tissot C, Povala G, Therriault J, Benedet AL, Ashton NJ, Servaes S, Chamoun M, Stevenson J, Rahmouni N, Vermeiren M, Macedo AC, Fernández-Lebrero A, García-Escobar G, Navalpotro-Gómez I, Lopez O, Tudorascu DL, Cohen A, Villemagne VL, Klunk WE, Gauthier S, Zimmer ER, Karikari TK, Blennow K, Zetterberg H, Suárez-Calvet M, Rosa-Neto P, Pascoal TA. Bellaver B, et al. Alzheimers Dement. 2023 Sep;19(9):3815-3825. doi: 10.1002/alz.13014. Epub 2023 Mar 15. Alzheimers Dement. 2023. PMID: 36919582
APOEε4 associates with microglial activation independently of Aβ plaques and tau tangles.
Ferrari-Souza JP, Lussier FZ, Leffa DT, Therriault J, Tissot C, Bellaver B, Ferreira PCL, Malpetti M, Wang YT, Povala G, Benedet AL, Ashton NJ, Chamoun M, Servaes S, Bezgin G, Kang MS, Stevenson J, Rahmouni N, Pallen V, Poltronetti NM, O'Brien JT, Rowe JB, Cohen AD, Lopez OL, Tudorascu DL, Karikari TK, Klunk WE, Villemagne VL, Soucy JP, Gauthier S, Souza DO, Zetterberg H, Blennow K, Zimmer ER, Rosa-Neto P, Pascoal TA. Ferrari-Souza JP, et al. Among authors: tudorascu dl. Sci Adv. 2023 Apr 5;9(14):eade1474. doi: 10.1126/sciadv.ade1474. Epub 2023 Apr 5. Sci Adv. 2023. PMID: 37018391 Free PMC article.
Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer's disease.
Bellaver B, Povala G, Ferreira PCL, Ferrari-Souza JP, Leffa DT, Lussier FZ, Benedet AL, Ashton NJ, Triana-Baltzer G, Kolb HC, Tissot C, Therriault J, Servaes S, Stevenson J, Rahmouni N, Lopez OL, Tudorascu DL, Villemagne VL, Ikonomovic MD, Gauthier S, Zimmer ER, Zetterberg H, Blennow K, Aizenstein HJ, Klunk WE, Snitz BE, Maki P, Thurston RC, Cohen AD, Ganguli M, Karikari TK, Rosa-Neto P, Pascoal TA. Bellaver B, et al. Among authors: tudorascu dl. Nat Med. 2023 Jul;29(7):1775-1781. doi: 10.1038/s41591-023-02380-x. Epub 2023 May 29. Nat Med. 2023. PMID: 37248300 Free PMC article.
The Association of Age-Related and Off-Target Retention with Longitudinal Quantification of [18F]MK6240 Tau PET in Target Regions.
Tissot C, Servaes S, Lussier FZ, Ferrari-Souza JP, Therriault J, Ferreira PCL, Bezgin G, Bellaver B, Leffa DT, Mathotaarachchi SS, Chamoun M, Stevenson J, Rahmouni N, Kang MS, Pallen V, Margherita-Poltronetti N, Wang YT, Fernandez-Arias J, Benedet AL, Zimmer ER, Soucy JP, Tudorascu DL, Cohen AD, Sharp M, Gauthier S, Massarweh G, Lopresti B, Klunk WE, Baker SL, Villemagne VL, Rosa-Neto P, Pascoal TA. Tissot C, et al. Among authors: tudorascu dl. J Nucl Med. 2023 Mar;64(3):452-459. doi: 10.2967/jnumed.122.264434. Epub 2022 Nov 17. J Nucl Med. 2023. PMID: 36396455 Free PMC article.
142 results