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A human peroxisome-proliferator-activated receptor-gamma is activated by inducers of adipogenesis, including thiazolidinedione drugs.
Lambe KG, Tugwood JD. Lambe KG, et al. Among authors: tugwood jd. Eur J Biochem. 1996 Jul 1;239(1):1-7. doi: 10.1111/j.1432-1033.1996.0001u.x. Eur J Biochem. 1996. PMID: 8706692
Peroxisome proliferator-activated receptor alpha: role in rodent liver cancer and species differences.
Holden PR, Tugwood JD. Holden PR, et al. Among authors: tugwood jd. J Mol Endocrinol. 1999 Feb;22(1):1-8. doi: 10.1677/jme.0.0220001. J Mol Endocrinol. 1999. PMID: 9924174 Review.
Dexamethasone and insulin demonstrate marked and opposite regulation of the steady-state mRNA level of the peroxisomal proliferator-activated receptor (PPAR) in hepatic cells. Hormonal modulation of fatty-acid-induced transcription.
Steineger HH, Sørensen HN, Tugwood JD, Skrede S, Spydevold O, Gautvik KM. Steineger HH, et al. Among authors: tugwood jd. Eur J Biochem. 1994 Nov 1;225(3):967-74. doi: 10.1111/j.1432-1033.1994.0967b.x. Eur J Biochem. 1994. PMID: 7957233
The peroxisome proliferator-activated receptor:retinoid X receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs.
Issemann I, Prince RA, Tugwood JD, Green S. Issemann I, et al. Among authors: tugwood jd. J Mol Endocrinol. 1993 Aug;11(1):37-47. doi: 10.1677/jme.0.0110037. J Mol Endocrinol. 1993. PMID: 8240670
Orphans await a real purpose in life.
Tugwood JD. Tugwood JD. Hum Exp Toxicol. 1996 Apr;15(4):363-4. doi: 10.1177/096032719601500415. Hum Exp Toxicol. 1996. PMID: 8845229 No abstract available.
Peroxisome proliferator-activated receptors: structures and function.
Tugwood JD, Aldridge TC, Lambe KG, Macdonald N, Woodyatt NJ. Tugwood JD, et al. Ann N Y Acad Sci. 1996 Dec 27;804:252-65. doi: 10.1111/j.1749-6632.1996.tb18620.x. Ann N Y Acad Sci. 1996. PMID: 8993548
The peroxisome proliferator (PP) response element upstream of the human acyl CoA oxidase gene is inactive among a sample human population: significance for species differences in response to PPs.
Woodyatt NJ, Lambe KG, Myers KA, Tugwood JD, Roberts RA. Woodyatt NJ, et al. Among authors: tugwood jd. Carcinogenesis. 1999 Mar;20(3):369-72. doi: 10.1093/carcin/20.3.369. Carcinogenesis. 1999. PMID: 10190548
Peroxisome proliferator-activated receptor (PPAR) alpha-regulated growth responses and their importance to hepatocarcinogenesis.
James NH, Gill JH, Brindle R, Woodyatt NJ, Macdonald N, Rolfe M, Hasmall SC, Tugwood JD, Holden PR, Roberts RA. James NH, et al. Among authors: tugwood jd. Toxicol Lett. 1998 Dec 28;102-103:91-6. doi: 10.1016/s0378-4274(98)00291-4. Toxicol Lett. 1998. PMID: 10022238 Review.
A peroxisome proliferator-activated receptor-alpha (PPARalpha) cDNA cloned from guinea-pig liver encodes a protein with similar properties to the mouse PPARalpha: implications for species differences in responses to peroxisome proliferators.
Tugwood JD, Holden PR, James NH, Prince RA, Roberts RA. Tugwood JD, et al. Arch Toxicol. 1998 Feb;72(3):169-77. doi: 10.1007/s002040050483. Arch Toxicol. 1998. PMID: 9520140
An epitope-tagging system for studying regulation of the peroxisome proliferator activated receptor alpha (PPAR alpha).
Owens JM, Tugwood JD, Gibson GG. Owens JM, et al. Among authors: tugwood jd. Eur J Drug Metab Pharmacokinet. 1997 Oct-Dec;22(4):325-8. doi: 10.1007/BF03190965. Eur J Drug Metab Pharmacokinet. 1997. PMID: 9512929
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