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ß3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells.
Tumbarello DA, Temple J, Brenton JD. Tumbarello DA, et al. Mol Cancer. 2012 May 28;11:36. doi: 10.1186/1476-4598-11-36. Mol Cancer. 2012. PMID: 22640878 Free PMC article.
Myosin VI and its cargo adaptors - linking endocytosis and autophagy.
Tumbarello DA, Kendrick-Jones J, Buss F. Tumbarello DA, et al. J Cell Sci. 2013 Jun 15;126(Pt 12):2561-70. doi: 10.1242/jcs.095554. Epub 2013 Jun 18. J Cell Sci. 2013. PMID: 23781020 Free PMC article. Review.
MYO6 Regulates Spatial Organization of Signaling Endosomes Driving AKT Activation and Actin Dynamics.
Masters TA, Tumbarello DA, Chibalina MV, Buss F. Masters TA, et al. Among authors: tumbarello da. Cell Rep. 2017 Jun 6;19(10):2088-2101. doi: 10.1016/j.celrep.2017.05.048. Cell Rep. 2017. PMID: 28591580 Free PMC article.
SPARC Regulates Transforming Growth Factor Beta Induced (TGFBI) Extracellular Matrix Deposition and Paclitaxel Response in Ovarian Cancer Cells.
Tumbarello DA, Andrews MR, Brenton JD. Tumbarello DA, et al. PLoS One. 2016 Sep 13;11(9):e0162698. doi: 10.1371/journal.pone.0162698. eCollection 2016. PLoS One. 2016. PMID: 27622658 Free PMC article.
Loss of cargo binding in the human myosin VI deafness mutant (R1166X) leads to increased actin filament binding.
Arden SD, Tumbarello DA, Butt T, Kendrick-Jones J, Buss F. Arden SD, et al. Among authors: tumbarello da. Biochem J. 2016 Oct 1;473(19):3307-19. doi: 10.1042/BCJ20160571. Epub 2016 Jul 29. Biochem J. 2016. PMID: 27474411 Free PMC article.
Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome.
Tumbarello DA, Waxse BJ, Arden SD, Bright NA, Kendrick-Jones J, Buss F. Tumbarello DA, et al. Nat Cell Biol. 2012 Oct;14(10):1024-35. doi: 10.1038/ncb2589. Epub 2012 Sep 30. Nat Cell Biol. 2012. PMID: 23023224 Free PMC article.
Small-molecule inhibitors of myosin proteins.
Bond LM, Tumbarello DA, Kendrick-Jones J, Buss F. Bond LM, et al. Among authors: tumbarello da. Future Med Chem. 2013 Jan;5(1):41-52. doi: 10.4155/fmc.12.185. Future Med Chem. 2013. PMID: 23256812 Free PMC article. Review.
Paxillin is essential for PTP-PEST-dependent regulation of cell spreading and motility: a role for paxillin kinase linker.
Jamieson JS, Tumbarello DA, Hallé M, Brown MC, Tremblay ML, Turner CE. Jamieson JS, et al. Among authors: tumbarello da. J Cell Sci. 2005 Dec 15;118(Pt 24):5835-47. doi: 10.1242/jcs.02693. Epub 2005 Nov 29. J Cell Sci. 2005. PMID: 16317044
Ex-vivo models of the Retinal Pigment Epithelium (RPE) in long-term culture faithfully recapitulate key structural and physiological features of native RPE.
Lynn SA, Ward G, Keeling E, Scott JA, Cree AJ, Johnston DA, Page A, Cuan-Urquizo E, Bhaskar A, Grossel MC, Tumbarello DA, Newman TA, Lotery AJ, Ratnayaka JA. Lynn SA, et al. Among authors: tumbarello da. Tissue Cell. 2017 Aug;49(4):447-460. doi: 10.1016/j.tice.2017.06.003. Epub 2017 Jun 19. Tissue Cell. 2017. PMID: 28669519 Free PMC article.
Regulation of paxillin family members during epithelial-mesenchymal transformation: a putative role for paxillin delta.
Tumbarello DA, Brown MC, Hetey SE, Turner CE. Tumbarello DA, et al. J Cell Sci. 2005 Oct 15;118(Pt 20):4849-63. doi: 10.1242/jcs.02615. J Cell Sci. 2005. PMID: 16219691
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