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Inhibition of acetylcholinesterase, beta-amyloid aggregation, and NMDA receptors in Alzheimer's disease: a promising direction for the multi-target-directed ligands gold rush.
Rosini M, Simoni E, Bartolini M, Cavalli A, Ceccarini L, Pascu N, McClymont DW, Tarozzi A, Bolognesi ML, Minarini A, Tumiatti V, Andrisano V, Mellor IR, Melchiorre C. Rosini M, et al. Among authors: tumiatti v. J Med Chem. 2008 Aug 14;51(15):4381-4. doi: 10.1021/jm800577j. Epub 2008 Jul 8. J Med Chem. 2008. PMID: 18605718
Synthesis of monomeric derivatives to probe memoquin's bivalent interactions.
Bolognesi ML, Chiriano G, Bartolini M, Mancini F, Bottegoni G, Maestri V, Czvitkovich S, Windisch M, Cavalli A, Minarini A, Rosini M, Tumiatti V, Andrisano V, Melchiorre C. Bolognesi ML, et al. Among authors: tumiatti v. J Med Chem. 2011 Dec 22;54(24):8299-304. doi: 10.1021/jm200691d. Epub 2011 Nov 23. J Med Chem. 2011. PMID: 22054058
Multifunctional tacrine derivatives in Alzheimer's disease.
Minarini A, Milelli A, Simoni E, Rosini M, Bolognesi ML, Marchetti C, Tumiatti V. Minarini A, et al. Among authors: tumiatti v. Curr Top Med Chem. 2013;13(15):1771-86. doi: 10.2174/15680266113139990136. Curr Top Med Chem. 2013. PMID: 23931443 Review.
Tacrine derivatives and Alzheimer's disease.
Tumiatti V, Minarini A, Bolognesi ML, Milelli A, Rosini M, Melchiorre C. Tumiatti V, et al. Curr Med Chem. 2010;17(17):1825-38. doi: 10.2174/092986710791111206. Curr Med Chem. 2010. PMID: 20345341 Review.
83 results