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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1961 1
1975 1
1979 2
1980 6
1981 7
1982 10
1983 11
1984 29
1985 72
1986 208
1987 473
1988 803
1989 1215
1990 1676
1991 1975
1992 2393
1993 2647
1994 3070
1995 3349
1996 3630
1997 3857
1998 4012
1999 4519
2000 4945
2001 5310
2002 5527
2003 5958
2004 6355
2005 6828
2006 7036
2007 7274
2008 7693
2009 7945
2010 8476
2011 8846
2012 9425
2013 10134
2014 10159
2015 10358
2016 9688
2017 9823
2018 10024
2019 9889
2020 10433
2021 9974
2022 10796
2023 9048
2024 8455
2025 4357
2026 2

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223,852 results

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Page 1
TNF alpha and the TNF receptor superfamily: structure-function relationship(s).
Idriss HT, Naismith JH. Idriss HT, et al. Microsc Res Tech. 2000 Aug 1;50(3):184-95. doi: 10.1002/1097-0029(20000801)50:3<184::AID-JEMT2>3.0.CO;2-H. Microsc Res Tech. 2000. PMID: 10891884 Review.
Tumour Necrosis Factor alpha (TNF alpha), is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and is responsible for a diverse range of signalling events within cells, leading to necrosis or apoptosis. ...This …
Tumour Necrosis Factor alpha (TNF alpha), is an inflammatory cytokine produced by macrophages/monocytes during a …
Historical perspectives on tumor necrosis factor and its superfamily: 25 years later, a golden journey.
Aggarwal BB, Gupta SC, Kim JH. Aggarwal BB, et al. Blood. 2012 Jan 19;119(3):651-65. doi: 10.1182/blood-2011-04-325225. Epub 2011 Nov 3. Blood. 2012. PMID: 22053109 Free PMC article. Review.
Although activity that induced tumor regression was observed and termed tumor necrosis factor (TNF) as early as the 1960s, the true identity of TNF was not clear until 1984, when Aggarwal and coworkers reported, for the first time, the is …
Although activity that induced tumor regression was observed and termed tumor necrosis factor (TNF) as ea …
Inhibitors of tumor necrosis factor (TNF) in sarcoidosis: who, what, and how to use them.
Baughman RP, Lower EE, Drent M. Baughman RP, et al. Sarcoidosis Vasc Diffuse Lung Dis. 2008 Dec;25(2):76-89. Sarcoidosis Vasc Diffuse Lung Dis. 2008. PMID: 19382527 Review.
However disabling side effects which accompany prolonged treatment can necessitate the use of alternative, steroid-sparing agents. The tumor necrosis factor (TNF) inhibitors can be useful in treating chronic sarcoidosis. ...This review will summarize t …
However disabling side effects which accompany prolonged treatment can necessitate the use of alternative, steroid-sparing agents. The tu …
Divergent effects of tumor necrosis factor (TNF) in sepsis: a meta-analysis of experimental studies.
Kassasseya C, Torsin LI, Musset C, Benhamou M, Chaudry IH, Cavaillon JM, Grall N, Monteiro R, de Chaisemartin L, Longrois D, Montravers P, de Tymowski C. Kassasseya C, et al. Crit Care. 2024 Sep 4;28(1):293. doi: 10.1186/s13054-024-05057-0. Crit Care. 2024. PMID: 39227889 Free PMC article.
INTRODUCTION: Experimental studies in animals have yielded conflicting results on the role of Tumor Necrosis Factor (TNF) in sepsis and endotoxemia, with some reporting adaptive and others inappropriate effects. ...The main species used were mice (77%) …
INTRODUCTION: Experimental studies in animals have yielded conflicting results on the role of Tumor Necrosis Factor ( …
Cell death checkpoints in the TNF pathway.
Huyghe J, Priem D, Bertrand MJM. Huyghe J, et al. Trends Immunol. 2023 Aug;44(8):628-643. doi: 10.1016/j.it.2023.05.007. Epub 2023 Jun 23. Trends Immunol. 2023. PMID: 37357102 Review.
Tumor necrosis factor (TNF) plays a central role in orchestrating mammalian inflammatory responses. ...Death is not the default response to TNF sensing. Molecular brakes, or cell death checkpoints, actively repress TNF cytotoxicity to pro …
Tumor necrosis factor (TNF) plays a central role in orchestrating mammalian inflammatory responses. ...Death is …
Tumor necrosis factor.
Old LJ. Old LJ. Sci Am. 1988 May;258(5):59-60, 69-75. doi: 10.1038/scientificamerican0588-59. Sci Am. 1988. PMID: 3051354 Review.
In 1975 the author found an explanation: the infection stimulates the secretion of tumor necrosis factor (TNF), which has anticancer activity. Now TNF, an important regulator of inflammation and immunity, is in clinical trials as an anticancer d …
In 1975 the author found an explanation: the infection stimulates the secretion of tumor necrosis factor (TNF), …
Tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta).
Ruddle NH. Ruddle NH. Curr Opin Immunol. 1992 Jun;4(3):327-32. doi: 10.1016/0952-7915(92)90084-r. Curr Opin Immunol. 1992. PMID: 1329840 Review.
Distinctions between tumor necrosis factor, TNF-alpha, and lymphotoxin, TNF-beta, have previously been based on the differences between their protein sequences, biological activity, and molecular regulation. ...The past year has also seen the de …
Distinctions between tumor necrosis factor, TNF-alpha, and lymphotoxin, TNF-beta, have previously been ba …
Tumor Necrosis Factor-alpha: The Next Marker of Stroke.
Xue Y, Zeng X, Tu WJ, Zhao J. Xue Y, et al. Dis Markers. 2022 Feb 27;2022:2395269. doi: 10.1155/2022/2395269. eCollection 2022. Dis Markers. 2022. PMID: 35265224 Free PMC article. Review.
Numerous inflammatory factors, including tumor necrosis factor (TNF), are involved in this process. These inflammatory factors play a dual role during stroke, and their mechanisms are complex. ...In researches done over the last few years, tumor …
Numerous inflammatory factors, including tumor necrosis factor (TNF), are involved in this process. These inflam …
Tumor necrosis factors.
Goetz FW, Planas JV, MacKenzie S. Goetz FW, et al. Dev Comp Immunol. 2004 May 3;28(5):487-97. doi: 10.1016/j.dci.2003.09.008. Dev Comp Immunol. 2004. PMID: 15062645 Review.
Since the discovery of tumor necrosis factor (TNF) and lymphotoxin, many structurally related factors have been elucidated in mammals that are grouped together in the TNF Ligand Superfamily. ...TNF transcripts are expressed in both mammal …
Since the discovery of tumor necrosis factor (TNF) and lymphotoxin, many structurally related factors have been …
Epigallocatechin gallate attenuates tumor necrosis factor (TNF)-alpha-induced inhibition of osteoblastic differentiation by up-regulating lncRNA TUG1 in osteoporosis.
Han Y, Pei D, Li W, Luo B, Jiang Q. Han Y, et al. Bioengineered. 2022 Apr;13(4):8950-8961. doi: 10.1080/21655979.2022.2056825. Bioengineered. 2022. PMID: 35358011 Free PMC article.
This study was to investigate the effect and mechanism of epigallocatechin gallate (EGCG) on tumor necrosis factor (TNF)-alpha-caused inhibition of osteoblastic differentiation. First, we cultured mouse embryo osteoblast precursor cells (MC3T3-E1) and …
This study was to investigate the effect and mechanism of epigallocatechin gallate (EGCG) on tumor necrosis factor ( …
223,852 results
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