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Tumor necrosis factor-alpha. A mediator of focal ischemic brain injury.
Barone FC, Arvin B, White RF, Miller A, Webb CL, Willette RN, Lysko PG, Feuerstein GZ. Barone FC, et al. Stroke. 1997 Jun;28(6):1233-44. doi: 10.1161/01.str.28.6.1233. Stroke. 1997. PMID: 9183357
BACKGROUND AND PURPOSE: Tumor necrosis factor-alpha (TNF-alpha) is a pleiotropic cytokine that rapidly upregulates in the brain after injury. The present study was designed to explore the pathophysiological significance of brain
BACKGROUND AND PURPOSE: Tumor necrosis factor-alpha (TNF-alpha) is a pleiotropic cytokine that rapidly up …
Tumor necrosis factor is a brain damaging cytokine in cerebral ischemia.
Meistrell ME 3rd, Botchkina GI, Wang H, Di Santo E, Cockroft KM, Bloom O, Vishnubhakat JM, Ghezzi P, Tracey KJ. Meistrell ME 3rd, et al. Shock. 1997 Nov;8(5):341-8. Shock. 1997. PMID: 9361344
Two contrasting roles, one beneficial and the injurious, have been proposed for tumor necrosis factor (TNF) in the pathogenesis of cerebral ischemia. ...These findings establish an important, pathophysiological role of TNF in mediating the progr …
Two contrasting roles, one beneficial and the injurious, have been proposed for tumor necrosis factor (TNF) in the path …
Cytokines and perinatal brain injury.
Silverstein FS, Barks JD, Hagan P, Liu XH, Ivacko J, Szaflarski J. Silverstein FS, et al. Neurochem Int. 1997 Apr-May;30(4-5):375-83. doi: 10.1016/s0197-0186(96)00072-1. Neurochem Int. 1997. PMID: 9106251 Review.
A rapidly expanding body of data provides support for the hypothesis that pro-inflammatory cytokines including interleukin-1 beta (IL-1 beta), and tumor necrosis factor-alpha (TNF-alpha) are expressed acutely in injured brain and contribu …
A rapidly expanding body of data provides support for the hypothesis that pro-inflammatory cytokines including interleukin-1 beta (IL-1 beta …
Lipopolysaccharide pre-treatment induces resistance against subsequent focal cerebral ischemic damage in spontaneously hypertensive rats.
Tasaki K, Ruetzler CA, Ohtsuki T, Martin D, Nawashiro H, Hallenbeck JM. Tasaki K, et al. Brain Res. 1997 Feb 14;748(1-2):267-70. doi: 10.1016/s0006-8993(96)01383-2. Brain Res. 1997. PMID: 9067475
Ischemic tolerance was induced in spontaneously hypertensive rats (SHR) by injection of a single dose of lipopolysaccharide (LPS) (0.9 mg/kg, i.v.) 1-7 days prior to permanent middle cerebral artery occlusion (MCAO). ...On this basis, the tolerance to ischemia induc
Ischemic tolerance was induced in spontaneously hypertensive rats (SHR) by injection of a single dose of lipopolysaccharide (LPS) (0.
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