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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2007 1
2013 4
2014 4
2016 1
2018 2
2019 1
2021 1
2022 1
2023 0
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Page 1
Tumor vasculature and glioma stem cells: Contributions to glioma progression.
Jhaveri N, Chen TC, Hofman FM. Jhaveri N, et al. Cancer Lett. 2016 Oct 1;380(2):545-551. doi: 10.1016/j.canlet.2014.12.028. Epub 2014 Dec 16. Cancer Lett. 2016. PMID: 25527451 Review.
Recent studies suggest that while blood vessels support glioma stem cells, these tumor cells in turn may regulate and contribute to the tumor vasculature by transdifferentiating into endothelial cells directly …
Recent studies suggest that while blood vessels support glioma stem cells, these tumor cells in tu …
Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth.
Cheng L, Huang Z, Zhou W, Wu Q, Donnola S, Liu JK, Fang X, Sloan AE, Mao Y, Lathia JD, Min W, McLendon RE, Rich JN, Bao S. Cheng L, et al. Cell. 2013 Mar 28;153(1):139-52. doi: 10.1016/j.cell.2013.02.021. Cell. 2013. PMID: 23540695 Free PMC article.
Glioblastomas (GBMs) are highly vascular and lethal brain tumors that display cellular hierarchies containing self-renewing tumorigenic glioma stem cells (GSCs). ...Therapeutic targeting of GSC-derived pericytes may effectively block tumor pr …
Glioblastomas (GBMs) are highly vascular and lethal brain tumors that display cellular hierarchies containing self-renewing tumorigen …
VEGF in tumor progression and targeted therapy.
Chekhonin VP, Shein SA, Korchagina AA, Gurina OI. Chekhonin VP, et al. Curr Cancer Drug Targets. 2013 May;13(4):423-43. doi: 10.2174/15680096113139990074. Curr Cancer Drug Targets. 2013. PMID: 23167597 Review.
In addition, it contributes to enhanced tumor cell invasion into the normal brain. The mechanisms of resistance include activation of alternative proangiogenic signaling pathways, of an invasive population of tumor cells, metabolic change toward glycol …
In addition, it contributes to enhanced tumor cell invasion into the normal brain. The mechanisms of resistance include activa …
Glioblastoma: a pathogenic crosstalk between tumor cells and pericytes.
Caspani EM, Crossley PH, Redondo-Garcia C, Martinez S. Caspani EM, et al. PLoS One. 2014 Jul 17;9(7):e101402. doi: 10.1371/journal.pone.0101402. eCollection 2014. PLoS One. 2014. PMID: 25032689 Free PMC article.
Cancers likely originate in progenitor zones containing stem cells and perivascular stromal cells. Much evidence suggests stromal cells play a central role in tumor initiation and progression. ...Nevertheless, how pericytes contribute …
Cancers likely originate in progenitor zones containing stem cells and perivascular stromal cells. Much evidence sugges …
Autocrine factors that sustain glioma invasion and paracrine biology in the brain microenvironment.
Hoelzinger DB, Demuth T, Berens ME. Hoelzinger DB, et al. J Natl Cancer Inst. 2007 Nov 7;99(21):1583-93. doi: 10.1093/jnci/djm187. Epub 2007 Oct 30. J Natl Cancer Inst. 2007. PMID: 17971532 Review.
Conversely, normal brain parenchymal cells secrete ligands that can stimulate receptors on invasive glioma cells and potentially facilitate glioma invasion or create a permissive microenvironment for malignant progression. ...Key paracrine inter …
Conversely, normal brain parenchymal cells secrete ligands that can stimulate receptors on invasive glioma cells and po …
Vasculogenic mimicry: a novel target for glioma therapy.
Chen YS, Chen ZP. Chen YS, et al. Chin J Cancer. 2014 Feb;33(2):74-9. doi: 10.5732/cjc.012.10292. Epub 2013 Jul 2. Chin J Cancer. 2014. PMID: 23816560 Free PMC article. Review.
There is also evidence of a physiological connection between the endothelial-lined vasculature and VM channels. Tumor cells, by virtue of their high plasticity, can form vessel-like structures themselves, which may function as blood supply netwo …
There is also evidence of a physiological connection between the endothelial-lined vasculature and VM channels. Tumor cells …
NEO212, a conjugate of temozolomide and perillyl alcohol, blocks the endothelial-to-mesenchymal transition in tumor-associated brain endothelial cells in glioblastoma.
Marín-Ramos NI, Jhaveri N, Thein TZ, Fayngor RA, Chen TC, Hofman FM. Marín-Ramos NI, et al. Cancer Lett. 2019 Feb 1;442:170-180. doi: 10.1016/j.canlet.2018.10.034. Epub 2018 Oct 28. Cancer Lett. 2019. PMID: 30392789
As the endothelial-to-mesenchymal transition (EndMT) supports the pro-angiogenic and invasive characteristics of glioblastoma multiforme (GBM), blocking this process would be a promising approach to inhibit tumor progression and recurrence. Here, we demonstrate that …
As the endothelial-to-mesenchymal transition (EndMT) supports the pro-angiogenic and invasive characteristics of glioblastoma multiforme (GB …
Upregulated functional gene expression programmes in tumour pericytes mark progression in patients with low-grade glioma.
Oudenaarden C, Sjölund J, Pietras K. Oudenaarden C, et al. Mol Oncol. 2022 Jan;16(2):405-421. doi: 10.1002/1878-0261.13016. Epub 2021 Jun 5. Mol Oncol. 2022. PMID: 34018679 Free PMC article.
Pericytes conceivably play important roles in the tumour microenvironment of glioblastoma multiforme (GBM) by allowing for an aberrant vasculature and acting as a component in the perivascular niche that supports glioma stem-like cells. ...Most …
Pericytes conceivably play important roles in the tumour microenvironment of glioblastoma multiforme (GBM) by allowing for an aberran …
Oligodendrocyte progenitor cells promote neovascularization in glioma by disrupting the blood-brain barrier.
Huang Y, Hoffman C, Rajappa P, Kim JH, Hu W, Huse J, Tang Z, Li X, Weksler B, Bromberg J, Lyden DC, Greenfield JP. Huang Y, et al. Cancer Res. 2014 Feb 15;74(4):1011-21. doi: 10.1158/0008-5472.CAN-13-1072. Epub 2013 Dec 26. Cancer Res. 2014. PMID: 24371228
Enhanced platelet-derived growth factor (PDGF) signaling in glioma drives its development and progression. In this study, we define a unique role for stroma-derived PDGF signaling in maintaining tumor homeostasis within the glioma microenvironment. ... …
Enhanced platelet-derived growth factor (PDGF) signaling in glioma drives its development and progression. In this study, we d …
Combinatorial Effects of VEGFR Kinase Inhibitor Axitinib and Oncolytic Virotherapy in Mouse and Human Glioblastoma Stem-Like Cell Models.
Saha D, Wakimoto H, Peters CW, Antoszczyk SJ, Rabkin SD, Martuza RL. Saha D, et al. Clin Cancer Res. 2018 Jul 15;24(14):3409-3422. doi: 10.1158/1078-0432.CCR-17-1717. Epub 2018 Mar 29. Clin Cancer Res. 2018. PMID: 29599413 Free PMC article.
Purpose: Glioblastoma (GBM), a fatal brain cancer, contains a subpopulation of GBM stem-like cells (GSCs) that contribute to resistance to current therapy. Angiogenesis also plays a key role in GBM progression. Therefore, we developed a strategy to tar …
Purpose: Glioblastoma (GBM), a fatal brain cancer, contains a subpopulation of GBM stem-like cells (GSCs) that contribute …
11 results