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Tumors Alter Inflammation and Impair Dermal Wound Healing in Female Mice.
Pyter LM, Husain Y, Calero H, McKim DB, Lin HY, Godbout JP, Sheridan JF, Engeland CG, Marucha PT. Pyter LM, et al. PLoS One. 2016 Aug 22;11(8):e0161537. doi: 10.1371/journal.pone.0161537. eCollection 2016. PLoS One. 2016. PMID: 27548621 Free PMC article.
Previous work has emphasized the immunosuppressive effects of tumors on adaptive immunity and has shown that surgery incites cancer metastases. However, the extent to which and how tumors may alter the clinically-relevant innate immune process of wound
Previous work has emphasized the immunosuppressive effects of tumors on adaptive immunity and has shown that surgery incites cancer m …
Epigenetic memory of radiotherapy in dermal fibroblasts impairs wound repair capacity in cancer survivors.
Bian X, Piipponen M, Liu Z, Luo L, Geara J, Chen Y, Sangsuwan T, Maselli M, Diaz C, Bain CA, Eenjes E, Genander M, Crichton M, Cash JL, Archambault L, Haghdoost S, Fradette J, Sommar P, Halle M, Xu Landén N. Bian X, et al. Nat Commun. 2024 Oct 28;15(1):9286. doi: 10.1038/s41467-024-53295-1. Nat Commun. 2024. PMID: 39468077 Free PMC article.
Radiotherapy (RT), a common cancer treatment, unintentionally harms surrounding tissues, including the skin, and hinders wound healing years after treatment. This study aims to understand the mechanisms behind these late-onset adverse effects. ...Here we show that t …
Radiotherapy (RT), a common cancer treatment, unintentionally harms surrounding tissues, including the skin, and hinders wound hea