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Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis.
Niu G, Wright KL, Huang M, Song L, Haura E, Turkson J, Zhang S, Wang T, Sinibaldi D, Coppola D, Heller R, Ellis LM, Karras J, Bromberg J, Pardoll D, Jove R, Yu H. Niu G, et al. Among authors: turkson j. Oncogene. 2002 Mar 27;21(13):2000-8. doi: 10.1038/sj.onc.1205260. Oncogene. 2002. PMID: 11960372
Targeting STAT3 in cancer: how successful are we?
Yue P, Turkson J. Yue P, et al. Among authors: turkson j. Expert Opin Investig Drugs. 2009 Jan;18(1):45-56. doi: 10.1517/13543780802565791. Expert Opin Investig Drugs. 2009. PMID: 19053881 Free PMC article. Review.
Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells.
Gritsko T, Williams A, Turkson J, Kaneko S, Bowman T, Huang M, Nam S, Eweis I, Diaz N, Sullivan D, Yoder S, Enkemann S, Eschrich S, Lee JH, Beam CA, Cheng J, Minton S, Muro-Cacho CA, Jove R. Gritsko T, et al. Among authors: turkson j. Clin Cancer Res. 2006 Jan 1;12(1):11-9. doi: 10.1158/1078-0432.CCR-04-1752. Clin Cancer Res. 2006. PMID: 16397018
Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells.
Nam S, Buettner R, Turkson J, Kim D, Cheng JQ, Muehlbeyer S, Hippe F, Vatter S, Merz KH, Eisenbrand G, Jove R. Nam S, et al. Among authors: turkson j. Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):5998-6003. doi: 10.1073/pnas.0409467102. Epub 2005 Apr 18. Proc Natl Acad Sci U S A. 2005. PMID: 15837920 Free PMC article.
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