Turkson J - Search Results

1

Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine.

Carbone M, Amelio I, Affar EB, Brugarolas J, Cannon-Albright LA, Cantley LC, Cavenee WK, Chen Z, Croce CM, Andrea A, Gandara D, Giorgi C, Jia W, Lan Q, Mak TW, Manley JL, Mikoshiba K, Onuchic JN, Pass HI, Pinton P, Prives C, Rothman N, Sebti SM, Turkson J, Wu X, Yang H, Yu H, Melino G. Carbone M, et al. Among authors: turkson j. Cell Death Differ. 2018 Nov;25(11):1885-1904. doi: 10.1038/s41418-018-0213-5. Epub 2018 Oct 15. Cell Death Differ. 2018. PMID: 30323273 Free PMC article. Review.

2

Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation.

Turkson J, Ryan D, Kim JS, Zhang Y, Chen Z, Haura E, Laudano A, Sebti S, Hamilton AD, Jove R. Turkson J, et al. J Biol Chem. 2001 Nov 30;276(48):45443-55. doi: 10.1074/jbc.M107527200. Epub 2001 Sep 28. J Biol Chem. 2001. PMID: 11579100 Free article.

3

Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice.

Blaskovich MA, Sun J, Cantor A, Turkson J, Jove R, Sebti SM. Blaskovich MA, et al. Among authors: turkson j. Cancer Res. 2003 Mar 15;63(6):1270-9. Cancer Res. 2003. PMID: 12649187

4

Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity.

Turkson J, Kim JS, Zhang S, Yuan J, Huang M, Glenn M, Haura E, Sebti S, Hamilton AD, Jove R. Turkson J, et al. Mol Cancer Ther. 2004 Mar;3(3):261-9. Mol Cancer Ther. 2004. PMID: 15026546

5

Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity.

Turkson J, Zhang S, Palmer J, Kay H, Stanko J, Mora LB, Sebti S, Yu H, Jove R. Turkson J, et al. Mol Cancer Ther. 2004 Dec;3(12):1533-42. Mol Cancer Ther. 2004. PMID: 15634646

6

A novel platinum compound inhibits constitutive Stat3 signaling and induces cell cycle arrest and apoptosis of malignant cells.

Turkson J, Zhang S, Mora LB, Burns A, Sebti S, Jove R. Turkson J, et al. J Biol Chem. 2005 Sep 23;280(38):32979-88. doi: 10.1074/jbc.M502694200. Epub 2005 Jul 26. J Biol Chem. 2005. PMID: 16046414 Free article.

7

Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity.

Siddiquee K, Zhang S, Guida WC, Blaskovich MA, Greedy B, Lawrence HR, Yip ML, Jove R, McLaughlin MM, Lawrence NJ, Sebti SM, Turkson J. Siddiquee K, et al. Among authors: turkson j. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7391-6. doi: 10.1073/pnas.0609757104. Epub 2007 Apr 26. Proc Natl Acad Sci U S A. 2007. PMID: 17463090 Free PMC article.

8

An oxazole-based small-molecule Stat3 inhibitor modulates Stat3 stability and processing and induces antitumor cell effects.

Siddiquee KA, Gunning PT, Glenn M, Katt WP, Zhang S, Schrock C, Sebti SM, Jove R, Hamilton AD, Turkson J. Siddiquee KA, et al. Among authors: turkson j. ACS Chem Biol. 2007 Dec 21;2(12):787-98. doi: 10.1021/cb7001973. ACS Chem Biol. 2007. PMID: 18154266

9

Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein.

Turkson J, Bowman T, Adnane J, Zhang Y, Djeu JY, Sekharam M, Frank DA, Holzman LB, Wu J, Sebti S, Jove R. Turkson J, et al. Mol Cell Biol. 1999 Nov;19(11):7519-28. doi: 10.1128/MCB.19.11.7519. Mol Cell Biol. 1999. PMID: 10523640 Free PMC article.

10

A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction.

Demaria M, Giorgi C, Lebiedzinska M, Esposito G, D'Angeli L, Bartoli A, Gough DJ, Turkson J, Levy DE, Watson CJ, Wieckowski MR, Provero P, Pinton P, Poli V. Demaria M, et al. Among authors: turkson j. Aging (Albany NY). 2010 Nov;2(11):823-42. doi: 10.18632/aging.100232. Aging (Albany NY). 2010. PMID: 21084727 Free PMC article.

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