Application of stepwise discriminant analysis in the phenotyping of plasma cholinesterase variants

Ann Clin Biochem. 1985 Mar:22 ( Pt 2):175-8. doi: 10.1177/000456328502200213.

Abstract

Discriminant function analysis has been applied to the results of activity and inhibitor measurements carried out on a series of 229 specimens using benzoylcholine and butyrylthiocholine as substrate. The discriminant function was more effective in differentiating cholinesterase genotypes than either a single test or a combination of two tests.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzoylcholine
  • Butyrylthiocholine
  • Cholinesterase Inhibitors
  • Cholinesterases / blood
  • Cholinesterases / genetics*
  • Humans
  • Phenotype
  • Statistics as Topic
  • Substrate Specificity

Substances

  • Cholinesterase Inhibitors
  • Benzoylcholine
  • Butyrylthiocholine
  • Cholinesterases