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A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein.
Thijssen V, Hurdiss DL, Debski-Antoniak OJ, Spence MA, Franck C, Norman A, Aggarwal A, Mokiem NJ, van Dongen DAA, Vermeir SW, Liu M, Li W, Chatziandreou M, Donselaar T, Du W, Drulyte I, Bosch BJ, Snijder J, Turville SG, Payne RJ, Jackson CJ, van Kuppeveld FJM, Jongkees SAK. Thijssen V, et al. Proc Natl Acad Sci U S A. 2023 Jun 27;120(26):e2303292120. doi: 10.1073/pnas.2303292120. Epub 2023 Jun 20. Proc Natl Acad Sci U S A. 2023. PMID: 37339194 Free PMC article.
Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice.
Ashhurst AS, Johansen MD, Maxwell JWC, Stockdale S, Ashley CL, Aggarwal A, Siddiquee R, Miemczyk S, Nguyen DH, Mackay JP, Counoupas C, Byrne SN, Turville S, Steain M, Triccas JA, Hansbro PM, Payne RJ, Britton WJ. Ashhurst AS, et al. Among authors: turville s. Nat Commun. 2022 Nov 15;13(1):6972. doi: 10.1038/s41467-022-34297-3. Nat Commun. 2022. PMID: 36379950 Free PMC article.
Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs.
Loo L, Waller MA, Moreno CL, Cole AJ, Stella AO, Pop OT, Jochum AK, Ali OH, Denes CE, Hamoudi Z, Chung F, Aggarwal A, Low JKK, Patel K, Siddiquee R, Kang T, Mathivanan S, Mackay JP, Jochum W, Flatz L, Hesselson D, Turville S, Neely GG. Loo L, et al. Among authors: turville s. PLoS Biol. 2023 Feb 9;21(2):e3001967. doi: 10.1371/journal.pbio.3001967. eCollection 2023 Feb. PLoS Biol. 2023. PMID: 36757924 Free PMC article.
A persistent neutrophil-associated immune signature characterizes post-COVID-19 pulmonary sequelae.
George PM, Reed A, Desai SR, Devaraj A, Faiez TS, Laverty S, Kanwal A, Esneau C, Liu MKC, Kamal F, Man WD, Kaul S, Singh S, Lamb G, Faizi FK, Schuliga M, Read J, Burgoyne T, Pinto AL, Micallef J, Bauwens E, Candiracci J, Bougoussa M, Herzog M, Raman L, Ahmetaj-Shala B, Turville S, Aggarwal A, Farne HA, Dalla Pria A, Aswani AD, Patella F, Borek WE, Mitchell JA, Bartlett NW, Dokal A, Xu XN, Kelleher P, Shah A, Singanayagam A. George PM, et al. Among authors: turville s. Sci Transl Med. 2022 Nov 16;14(671):eabo5795. doi: 10.1126/scitranslmed.abo5795. Epub 2022 Nov 16. Sci Transl Med. 2022. PMID: 36383686 Free article.
Novel siRNA therapeutics demonstrate multi-variant efficacy against SARS-CoV-2.
Bowden-Reid E, Ledger S, Zhang Y, Di Giallonardo F, Aggarwal A, Stella AO, Akerman A, Milogiannakis V, Walker G, Rawlinson W, Turville S, Kelleher AD, Ahlenstiel C. Bowden-Reid E, et al. Among authors: turville s. Antiviral Res. 2023 Sep;217:105677. doi: 10.1016/j.antiviral.2023.105677. Epub 2023 Jul 20. Antiviral Res. 2023. PMID: 37478918 Free article.
Humoral and cellular immunity to SARS-CoV-2 Ancestral and Omicron BA.5 variants following vaccination in myelofibrosis patients.
Alcheikh A, Perkins GB, Pucar PA, Cecchin A, Chai CS, Tunbridge M, Akerman A, Aggarwal A, Milogiannakis V, Turville S, Allen S, Hissaria P, Banovic T, Coates PT, Ross DM. Alcheikh A, et al. Among authors: turville s. Blood Cancer J. 2023 Apr 10;13(1):50. doi: 10.1038/s41408-023-00824-8. Blood Cancer J. 2023. PMID: 37032391 Free PMC article. No abstract available.
105 results