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TNF-α-induced protein 3 is a key player in childhood asthma development and environment-mediated protection.
Krusche J, Twardziok M, Rehbach K, Böck A, Tsang MS, Schröder PC, Kumbrink J, Kirchner T, Xing Y, Riedler J, Dalphin JC, Pekkanen J, Lauener R, Roponen M, Li J, Wong CK, Wong GWK, Schaub B; PASTURE study group. Krusche J, et al. Among authors: twardziok m. J Allergy Clin Immunol. 2019 Dec;144(6):1684-1696.e12. doi: 10.1016/j.jaci.2019.07.029. Epub 2019 Aug 2. J Allergy Clin Immunol. 2019. PMID: 31381928 Clinical Trial.
Asthmatic farm children show increased CD3+CD8low T-cells compared to non-asthmatic farm children.
Twardziok M, Schröder PC, Krusche J, Casaca VI, Illi S, Böck A, Loss GJ, Kabesch M, Toncheva AA, Roduit C, Depner M, Genuneit J, Renz H, Roponen M, Weber J, Braun-Fahrländer C, Riedler J, Lauener R, Vuitton DA, Dalphin JC, Pekkanen J, von Mutius E, Schaub B; PASTURE Study Group:; Hyvärinen A, Karvonen AM, Kirjavainen PV, Remes S, Kaulek V, Dalphin ML, Ege M, Pfefferle PI, Doekes G. Twardziok M, et al. Clin Immunol. 2017 Oct;183:285-292. doi: 10.1016/j.clim.2017.09.009. Epub 2017 Sep 13. Clin Immunol. 2017. PMID: 28917722 No abstract available.