Single-cell transcriptomics reveals prominent expression of IL-14, IL-18, and IL-32 in psoriasis.
Frost B, Schmidt M, Klein B, Loeffler-Wirth H, Krohn K, Reidenbach T, Binder H, Stubenvoll A, Simon JC, Saalbach A, Kunz M.
Frost B, et al.
Eur J Immunol. 2023 Nov;53(11):e2250354. doi: 10.1002/eji.202250354. Epub 2023 Aug 20.
Eur J Immunol. 2023.
PMID: 37540729
RESULTS: Several different immune-activated cell types with particular cytokine patterns are identified such as keratinocytes, T-helper cells, dendritic cells, macrophages, and fibroblasts. Apart from well-known factors, IL-14 (TXLNA), IL-18, and IL-32 are identified with …
RESULTS: Several different immune-activated cell types with particular cytokine patterns are identified such as keratinocytes, T-helper cell …