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Cocaine promotes both initiation and elongation phase of HIV-1 transcription by activating NF-κB and MSK1 and inducing selective epigenetic modifications at HIV-1 LTR.
Sahu G, Farley K, El-Hage N, Aiamkitsumrit B, Fassnacht R, Kashanchi F, Ochem A, Simon GL, Karn J, Hauser KF, Tyagi M. Sahu G, et al. Among authors: tyagi m. Virology. 2015 Sep;483:185-202. doi: 10.1016/j.virol.2015.03.036. Epub 2015 May 15. Virology. 2015. PMID: 25980739 Free PMC article.
Varying modulation of HIV-1 LTR activity by Baf complexes.
Van Duyne R, Guendel I, Narayanan A, Gregg E, Shafagati N, Tyagi M, Easley R, Klase Z, Nekhai S, Kehn-Hall K, Kashanchi F. Van Duyne R, et al. Among authors: tyagi m. J Mol Biol. 2011 Aug 19;411(3):581-96. doi: 10.1016/j.jmb.2011.06.001. Epub 2011 Jun 15. J Mol Biol. 2011. PMID: 21699904 Free PMC article.
The effects of cocaine on HIV transcription.
Tyagi M, Weber J, Bukrinsky M, Simon GL. Tyagi M, et al. J Neurovirol. 2016 Jun;22(3):261-74. doi: 10.1007/s13365-015-0398-z. Epub 2015 Nov 16. J Neurovirol. 2016. PMID: 26572787 Free PMC article. Review.
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