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Page 1
FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons.
Ho WY, Chak LL, Hor JH, Liu F, Diaz-Garcia S, Chang JC, Sanford E, Rodriguez MJ, Alagappan D, Lim SM, Cho YL, Shimizu Y, Sun AX, Tyan SH, Koo E, Kim SH, Ravits J, Ng SY, Okamura K, Ling SC. Ho WY, et al. Among authors: tyan sh. iScience. 2023 Oct 6;26(11):108152. doi: 10.1016/j.isci.2023.108152. eCollection 2023 Nov 17. iScience. 2023. PMID: 37920668 Free PMC article.
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis.
Ling SC, Dastidar SG, Tokunaga S, Ho WY, Lim K, Ilieva H, Parone PA, Tyan SH, Tse TM, Chang JC, Platoshyn O, Bui NB, Bui A, Vetto A, Sun S, McAlonis-Downes M, Han JS, Swing D, Kapeli K, Yeo GW, Tessarollo L, Marsala M, Shaw CE, Tucker-Kellogg G, La Spada AR, Lagier-Tourenne C, Da Cruz S, Cleveland DW. Ling SC, et al. Among authors: tyan sh. Elife. 2019 Feb 12;8:e40811. doi: 10.7554/eLife.40811. Elife. 2019. PMID: 30747709 Free PMC article.
Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits.
Ho WY, Agrawal I, Tyan SH, Sanford E, Chang WT, Lim K, Ong J, Tan BSY, Moe AAK, Yu R, Wong P, Tucker-Kellogg G, Koo E, Chuang KH, Ling SC. Ho WY, et al. Among authors: tyan sh. Acta Neuropathol Commun. 2021 Jan 6;9(1):9. doi: 10.1186/s40478-020-01111-4. Acta Neuropathol Commun. 2021. PMID: 33407930 Free PMC article.
25 results