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A common mutation (G-455--> A) in the beta-fibrinogen promoter is an independent predictor of plasma fibrinogen, but not of ischemic heart disease. A study of 9,127 individuals based on the Copenhagen City Heart Study.
Tybjaerg-Hansen A, Agerholm-Larsen B, Humphries SE, Abildgaard S, Schnohr P, Nordestgaard BG. Tybjaerg-Hansen A, et al. J Clin Invest. 1997 Jun 15;99(12):3034-9. doi: 10.1172/JCI119499. J Clin Invest. 1997. PMID: 9185528 Free PMC article.
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