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Control of pre-T cell proliferation and differentiation by the GTPase Rac-I.
Gomez M, Tybulewicz V, Cantrell DA. Gomez M, et al. Among authors: tybulewicz v. Nat Immunol. 2000 Oct;1(4):348-52. doi: 10.1038/79808. Nat Immunol. 2000. PMID: 11017108
Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration.
Wells CM, Walmsley M, Ooi S, Tybulewicz V, Ridley AJ. Wells CM, et al. Among authors: tybulewicz v. J Cell Sci. 2004 Mar 1;117(Pt 7):1259-68. doi: 10.1242/jcs.00997. J Cell Sci. 2004. PMID: 14996945
Syk tyrosine kinase is critical for B cell antibody responses and memory B cell survival.
Ackermann JA, Nys J, Schweighoffer E, McCleary S, Smithers N, Tybulewicz VL. Ackermann JA, et al. J Immunol. 2015 May 15;194(10):4650-6. doi: 10.4049/jimmunol.1500461. Epub 2015 Apr 10. J Immunol. 2015. PMID: 25862820 Free PMC article.
WNK1 kinase balances T cell adhesion versus migration in vivo.
Köchl R, Thelen F, Vanes L, Brazão TF, Fountain K, Xie J, Huang CL, Lyck R, Stein JV, Tybulewicz VL. Köchl R, et al. Among authors: tybulewicz vl. Nat Immunol. 2016 Sep;17(9):1075-83. doi: 10.1038/ni.3495. Epub 2016 Jul 11. Nat Immunol. 2016. PMID: 27400149 Free PMC article.
Signalling through the TCR.
Cantrell D, Bluestone J, Vivier E, Tybulewicz V. Cantrell D, et al. Among authors: tybulewicz v. Res Immunol. 1998 Nov-Dec;149(9):866-7. doi: 10.1016/s0923-2494(99)80014-5. Res Immunol. 1998. PMID: 9923642 No abstract available.
Syk-dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan.
Slack EC, Robinson MJ, Hernanz-Falcón P, Brown GD, Williams DL, Schweighoffer E, Tybulewicz VL, Reis e Sousa C. Slack EC, et al. Eur J Immunol. 2007 Jun;37(6):1600-12. doi: 10.1002/eji.200636830. Eur J Immunol. 2007. PMID: 17458858
Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection.
Robinson MJ, Osorio F, Rosas M, Freitas RP, Schweighoffer E, Gross O, Verbeek JS, Ruland J, Tybulewicz V, Brown GD, Moita LF, Taylor PR, Reis e Sousa C. Robinson MJ, et al. Among authors: tybulewicz v. J Exp Med. 2009 Aug 31;206(9):2037-51. doi: 10.1084/jem.20082818. Epub 2009 Aug 24. J Exp Med. 2009. PMID: 19703985 Free PMC article.
Proteolysis of NF-kappaB1 p105 is essential for T cell antigen receptor-induced proliferation.
Sriskantharajah S, Belich MP, Papoutsopoulou S, Janzen J, Tybulewicz V, Seddon B, Ley SC. Sriskantharajah S, et al. Among authors: tybulewicz v. Nat Immunol. 2009 Jan;10(1):38-47. doi: 10.1038/ni.1685. Epub 2008 Dec 7. Nat Immunol. 2009. PMID: 19060899
Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17.
LeibundGut-Landmann S, Gross O, Robinson MJ, Osorio F, Slack EC, Tsoni SV, Schweighoffer E, Tybulewicz V, Brown GD, Ruland J, Reis e Sousa C. LeibundGut-Landmann S, et al. Among authors: tybulewicz v. Nat Immunol. 2007 Jun;8(6):630-8. doi: 10.1038/ni1460. Epub 2007 Apr 22. Nat Immunol. 2007. PMID: 17450144
Inefficient clustering of tyrosine-phosphorylated proteins at the immunological synapse in response to an antagonist peptide.
Smyth LA, Ardouin L, Williams O, Norton T, Tybulewicz V, Kioussis D. Smyth LA, et al. Among authors: tybulewicz v. Eur J Immunol. 2002 Dec;32(12):3386-94. doi: 10.1002/1521-4141(200212)32:12<3386::AID-IMMU3386>3.0.CO;2-W. Eur J Immunol. 2002. PMID: 12432569
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