Tyndale RF - Search Results

1

Ethnic variation in CYP2A6 and association of genetically slow nicotine metabolism and smoking in adult Caucasians.

Schoedel KA, Hoffmann EB, Rao Y, Sellers EM, Tyndale RF. Schoedel KA, et al. Among authors: tyndale rf. Pharmacogenetics. 2004 Sep;14(9):615-26. doi: 10.1097/00008571-200409000-00006. Pharmacogenetics. 2004. PMID: 15475735

2

Catalytic and immunologic similarities between monkey and human liver cytochrome P-450db1 (human cytochrome P-450 2D6).

Otton SV, Tyndale RF, Wu D, Inaba T, Kalow W, Sellers EM. Otton SV, et al. Among authors: tyndale rf. Drug Metab Dispos. 1992 Jan-Feb;20(1):1-5. Drug Metab Dispos. 1992. PMID: 1346982

3

Identification of a new variant CYP2D6 allele lacking the codon encoding Lys-281: possible association with the poor metabolizer phenotype.

Tyndale R, Aoyama T, Broly F, Matsunaga T, Inaba T, Kalow W, Gelboin HV, Meyer UA, Gonzalez FJ. Tyndale R, et al. Pharmacogenetics. 1991 Oct;1(1):26-32. doi: 10.1097/00008571-199110000-00005. Pharmacogenetics. 1991. PMID: 1844820

4

Neuronal cytochrome P450IID1 (debrisoquine/sparteine-type): potent inhibition of activity by (-)-cocaine and nucleotide sequence identity to human hepatic P450 gene CYP2D6.

Tyndale RF, Sunahara R, Inaba T, Kalow W, Gonzalez FJ, Niznik HB. Tyndale RF, et al. Mol Pharmacol. 1991 Jul;40(1):63-8. Mol Pharmacol. 1991. PMID: 1857341

5

Evidence in humans for variant allozymes of the nondeficient sparteine/debrisoquine monooxygenase (P45OIID 1) in vitro.

Tyndale RF, Inaba T, Kalow W. Tyndale RF, et al. Drug Metab Dispos. 1989 May-Jun;17(3):334-40. Drug Metab Dispos. 1989. PMID: 2568917

6

CYP2D6 phenotype and genotype in a Canadian Native Indian population.

Nowak MP, Tyndale RF, Sellers EM. Nowak MP, et al. Among authors: tyndale rf. Pharmacogenetics. 1997 Apr;7(2):145-8. doi: 10.1097/00008571-199704000-00008. Pharmacogenetics. 1997. PMID: 9170152 No abstract available.

7

A major role for CYP2A6 in nicotine C-oxidation by human liver microsomes.

Messina ES, Tyndale RF, Sellers EM. Messina ES, et al. Among authors: tyndale rf. J Pharmacol Exp Ther. 1997 Sep;282(3):1608-14. J Pharmacol Exp Ther. 1997. PMID: 9316878

8

Genetically deficient CYP2D6 metabolism provides protection against oral opiate dependence.

Tyndale RF, Droll KP, Sellers EM. Tyndale RF, et al. Pharmacogenetics. 1997 Oct;7(5):375-9. doi: 10.1097/00008571-199710000-00006. Pharmacogenetics. 1997. PMID: 9352573

9

Nicotine metabolism defect reduces smoking.

Pianezza ML, Sellers EM, Tyndale RF. Pianezza ML, et al. Among authors: tyndale rf. Nature. 1998 Jun 25;393(6687):750. doi: 10.1038/31623. Nature. 1998. PMID: 9655391 No abstract available.

10

NAD(P)H:quinone oxidoreductase: polymorphisms and allele frequencies in Caucasian, Chinese and Canadian Native Indian and Inuit populations.

Gaedigk A, Tyndale RF, Jurima-Romet M, Sellers EM, Grant DM, Leeder JS. Gaedigk A, et al. Among authors: tyndale rf. Pharmacogenetics. 1998 Aug;8(4):305-13. doi: 10.1097/00008571-199808000-00004. Pharmacogenetics. 1998. PMID: 9731717

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