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Page 1
BRCA2-branching out too?
Spitz MR, Liu Y, Amos CI. Spitz MR, et al. J Natl Cancer Inst. 2015 Apr 2;107(5):djv066. doi: 10.1093/jnci/djv066. Print 2015 May. J Natl Cancer Inst. 2015. PMID: 25838449 No abstract available.
A recurrent mutation in PARK2 is associated with familial lung cancer.
Xiong D, Wang Y, Kupert E, Simpson C, Pinney SM, Gaba CR, Mandal D, Schwartz AG, Yang P, de Andrade M, Pikielny C, Byun J, Li Y, Stambolian D, Spitz MR, Liu Y, Amos CI, Bailey-Wilson JE, Anderson M, You M. Xiong D, et al. Am J Hum Genet. 2015 Feb 5;96(2):301-8. doi: 10.1016/j.ajhg.2014.12.016. Epub 2015 Jan 29. Am J Hum Genet. 2015. PMID: 25640678 Free PMC article.
Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer.
Liu P, Vikis HG, Wang D, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Gazdar A, Gaba C, Rothschild H, Mandal D, Coons T, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Wu X, Spitz MR, Eisen T, Houlston RS, Amos CI, Anderson MW, You M. Liu P, et al. J Natl Cancer Inst. 2008 Sep 17;100(18):1326-30. doi: 10.1093/jnci/djn268. Epub 2008 Sep 9. J Natl Cancer Inst. 2008. PMID: 18780872 Free PMC article.
EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity.
Vikis H, Sato M, James M, Wang D, Wang Y, Wang M, Jia D, Liu Y, Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Yang P, Wiest JS, Fain PR, Schwartz AG, Gazdar A, Gaba C, Rothschild H, Mandal D, Kupert E, Seminara D, Viswanathan A, Govindan R, Minna J, Anderson MW, You M. Vikis H, et al. Cancer Res. 2007 May 15;67(10):4665-70. doi: 10.1158/0008-5472.CAN-07-0217. Cancer Res. 2007. PMID: 17510392 Free PMC article.
Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1.
Liu Y, Liu P, Wen W, James MA, Wang Y, Bailey-Wilson JE, Amos CI, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Schwartz AG, Gazdar A, Gaba C, Rothschild H, Mandal D, Kupert E, Lee J, Seminara D, Minna J, Anderson MW, You M. Liu Y, et al. Cancer Res. 2009 Oct 1;69(19):7844-50. doi: 10.1158/0008-5472.CAN-09-1833. Epub 2009 Sep 29. Cancer Res. 2009. PMID: 19789337 Free PMC article.
EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk.
Wilson IM, Vucic EA, Enfield KS, Thu KL, Zhang YA, Chari R, Lockwood WW, Radulovich N, Starczynowski DT, Banáth JP, Zhang M, Pusic A, Fuller M, Lonergan KM, Rowbotham D, Yee J, English JC, Buys TP, Selamat SA, Laird-Offringa IA, Liu P, Anderson M, You M, Tsao MS, Brown CJ, Bennewith KL, MacAulay CE, Karsan A, Gazdar AF, Lam S, Lam WL. Wilson IM, et al. Oncogene. 2014 Sep 4;33(36):4464-73. doi: 10.1038/onc.2013.396. Epub 2013 Oct 7. Oncogene. 2014. PMID: 24096489 Free PMC article.
A second genetic variant on chromosome 15q24-25.1 associates with lung cancer.
Liu P, Yang P, Wu X, Vikis HG, Lu Y, Wang Y, Schwartz AG, Pinney SM, de Andrade M, Gazdar A, Gaba C, Mandal D, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Spitz M, Amos CI, Anderson MW, You M. Liu P, et al. Cancer Res. 2010 Apr 15;70(8):3128-35. doi: 10.1158/0008-5472.CAN-09-3583. Cancer Res. 2010. PMID: 20395203 Free PMC article.
Cumulative effect of multiple loci on genetic susceptibility to familial lung cancer.
Liu P, Vikis HG, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Gazdar A, Gaba C, Mandal D, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Amos CI, Anderson MW, You M. Liu P, et al. Cancer Epidemiol Biomarkers Prev. 2010 Feb;19(2):517-24. doi: 10.1158/1055-9965.EPI-09-0791. Cancer Epidemiol Biomarkers Prev. 2010. PMID: 20142248 Free PMC article.
Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene.
You M, Wang D, Liu P, Vikis H, James M, Lu Y, Wang Y, Wang M, Chen Q, Jia D, Liu Y, Wen W, Yang P, Sun Z, Pinney SM, Zheng W, Shu XO, Long J, Gao YT, Xiang YB, Chow WH, Rothman N, Petersen GM, de Andrade M, Wu Y, Cunningham JM, Wiest JS, Fain PR, Schwartz AG, Girard L, Gazdar A, Gaba C, Rothschild H, Mandal D, Coons T, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Amos CI, Anderson MW. You M, et al. Clin Cancer Res. 2009 Apr 15;15(8):2666-74. doi: 10.1158/1078-0432.CCR-08-2335. Epub 2009 Apr 7. Clin Cancer Res. 2009. PMID: 19351763 Free PMC article.