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The citicoline brain injury treatment (COBRIT) trial: design and methods.
Zafonte R, Friedewald WT, Lee SM, Levin B, Diaz-Arrastia R, Ansel B, Eisenberg H, Timmons SD, Temkin N, Novack T, Ricker J, Merchant R, Jallo J. Zafonte R, et al. J Neurotrauma. 2009 Dec;26(12):2207-16. doi: 10.1089/neu.2009.1015. J Neurotrauma. 2009. PMID: 19803786 Free PMC article. Clinical Trial.
Effect of citicoline on functional and cognitive status among patients with traumatic brain injury: Citicoline Brain Injury Treatment Trial (COBRIT).
Zafonte RD, Bagiella E, Ansel BM, Novack TA, Friedewald WT, Hesdorffer DC, Timmons SD, Jallo J, Eisenberg H, Hart T, Ricker JH, Diaz-Arrastia R, Merchant RE, Temkin NR, Melton S, Dikmen SS. Zafonte RD, et al. JAMA. 2012 Nov 21;308(19):1993-2000. doi: 10.1001/jama.2012.13256. JAMA. 2012. PMID: 23168823 Clinical Trial.