U19 CA067771/CA/NCI NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
1998	1
1999	1
2000	1
2003	2
2004	1
2005	1
2006	2
2007	1
2008	2
2009	7
2010	9
2011	7
2012	4
2013	2
2014	1
2021	1
2022	1
2024	0

1

Aberrant Expression and Subcellular Localization of ECT2 Drives Colorectal Cancer Progression and Growth.

Cook DR, Kang M, Martin TD, Galanko JA, Loeza GH, Trembath DG, Justilien V, Pickering KA, Vincent DF, Jarosch A, Jurmeister P, Waters AM, Hibshman PS, Campbell AD, Ford CA, Keku TO, Yeh JJ, Lee MS, Cox AD, Fields AP, Sandler RS, Sansom OJ, Sers C, Schaefer A, Der CJ. Cook DR, et al. Cancer Res. 2022 Jan 1;82(1):90-104. doi: 10.1158/0008-5472.CAN-20-4218. Epub 2021 Nov 4. Cancer Res. 2022. PMID: 34737214 Free PMC article.

2

The RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin Contractility.

Mitin N, Rossman KL, Currin R, Anne S, Marshall TW, Bear JE, Bautch VL, Der CJ. Mitin N, et al. PLoS One. 2013 Jun 18;8(6):e66260. doi: 10.1371/journal.pone.0066260. Print 2013. PLoS One. 2013. PMID: 23825001 Free PMC article.

3

Identification of novel ROCK inhibitors with anti-migratory and anti-invasive activities.

Patel RA, Liu Y, Wang B, Li R, Sebti SM. Patel RA, et al. Oncogene. 2014 Jan 30;33(5):550-5. doi: 10.1038/onc.2012.634. Epub 2013 Feb 11. Oncogene. 2014. PMID: 23396364 Free PMC article.

4

Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2).

Pireddu R, Forinash KD, Sun NN, Martin MP, Sung SS, Alexander B, Zhu JY, Guida WC, Schönbrunn E, Sebti SM, Lawrence NJ. Pireddu R, et al. Medchemcomm. 2012 Jun 1;3(6):699-709. doi: 10.1039/C2MD00320A. Epub 2012 Jan 27. Medchemcomm. 2012. PMID: 23275831 Free PMC article.

5

ROCK1 and ROCK2 are required for non-small cell lung cancer anchorage-independent growth and invasion.

Vigil D, Kim TY, Plachco A, Garton AJ, Castaldo L, Pachter JA, Dong H, Chen X, Tokar B, Campbell SL, Der CJ. Vigil D, et al. Cancer Res. 2012 Oct 15;72(20):5338-47. doi: 10.1158/0008-5472.CAN-11-2373. Epub 2012 Aug 31. Cancer Res. 2012. PMID: 22942252 Free PMC article.

6

RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer.

Patel RA, Forinash KD, Pireddu R, Sun Y, Sun N, Martin MP, Schönbrunn E, Lawrence NJ, Sebti SM. Patel RA, et al. Cancer Res. 2012 Oct 1;72(19):5025-34. doi: 10.1158/0008-5472.CAN-12-0954. Epub 2012 Jul 30. Cancer Res. 2012. PMID: 22846914 Free PMC article.

7

The ect2 rho Guanine nucleotide exchange factor is essential for early mouse development and normal cell cytokinesis and migration.

Cook DR, Solski PA, Bultman SJ, Kauselmann G, Schoor M, Kuehn R, Friedman LS, Cowley DO, Van Dyke T, Yeh JJ, Johnson L, Der CJ. Cook DR, et al. Genes Cancer. 2011 Oct;2(10):932-42. doi: 10.1177/1947601912437035. Genes Cancer. 2011. PMID: 22701760 Free PMC article.

8

Fragment-based and structure-guided discovery and optimization of Rho kinase inhibitors.

Li R, Martin MP, Liu Y, Wang B, Patel RA, Zhu JY, Sun N, Pireddu R, Lawrence NJ, Li J, Haura EB, Sung SS, Guida WC, Schonbrunn E, Sebti SM. Li R, et al. J Med Chem. 2012 Mar 8;55(5):2474-8. doi: 10.1021/jm201289r. Epub 2012 Feb 15. J Med Chem. 2012. PMID: 22272748 Free PMC article.

9

RhoGDI2 antagonizes ovarian carcinoma growth, invasion and metastasis.

Stevens EV, Banet N, Onesto C, Plachco A, Alan JK, Nikolaishvili-Feinberg N, Midkiff BR, Kuan PF, Liu J, Miller CR, Vigil D, Graves LM, Der CJ. Stevens EV, et al. Small GTPases. 2011 Jul;2(4):202-210. doi: 10.4161/sgtp.2.4.17795. Epub 2011 Jul 1. Small GTPases. 2011. PMID: 22145092 Free PMC article.

10

Measurement of protein farnesylation and geranylgeranylation in vitro, in cultured cells and in biopsies, and the effects of prenyl transferase inhibitors.

Berndt N, Sebti SM. Berndt N, et al. Nat Protoc. 2011 Oct 27;6(11):1775-91. doi: 10.1038/nprot.2011.387. Nat Protoc. 2011. PMID: 22036881 Free PMC article.

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