U54 AI150472/AI/NIAID NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2018	3
2019	12
2020	15
2021	1

1

Structural basis for strand-transfer inhibitor binding to HIV intasomes.

Passos DO, Li M, Jóźwik IK, Zhao XZ, Santos-Martins D, Yang R, Smith SJ, Jeon Y, Forli S, Hughes SH, Burke TR Jr, Craigie R, Lyumkis D. Passos DO, et al. Science. 2020 Feb 14;367(6479):810-814. doi: 10.1126/science.aay8015. Epub 2020 Jan 30. Science. 2020. PMID: 32001521 Free PMC article.

2

Structural and mechanistic bases for a potent HIV-1 capsid inhibitor.

Bester SM, Wei G, Zhao H, Adu-Ampratwum D, Iqbal N, Courouble VV, Francis AC, Annamalai AS, Singh PK, Shkriabai N, Van Blerkom P, Morrison J, Poeschla EM, Engelman AN, Melikyan GB, Griffin PR, Fuchs JR, Asturias FJ, Kvaratskhelia M. Bester SM, et al. Science. 2020 Oct 16;370(6514):360-364. doi: 10.1126/science.abb4808. Science. 2020. PMID: 33060363

3

Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes.

Ozog S, Timberlake ND, Hermann K, Garijo O, Haworth KG, Shi G, Glinkerman CM, Schefter LE, D'Souza S, Simpson E, Sghia-Hughes G, Carillo RR, Boger DL, Kiem HP, Slukvin I, Ryu BY, Sorrentino BP, Adair JE, Snyder SA, Compton AA, Torbett BE. Ozog S, et al. Blood. 2019 Oct 17;134(16):1298-1311. doi: 10.1182/blood.2019000040. Blood. 2019. PMID: 31416800 Free PMC article.

4

HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains.

Francis AC, Marin M, Singh PK, Achuthan V, Prellberg MJ, Palermino-Rowland K, Lan S, Tedbury PR, Sarafianos SG, Engelman AN, Melikyan GB. Francis AC, et al. Nat Commun. 2020 Jul 14;11(1):3505. doi: 10.1038/s41467-020-17256-8. Nat Commun. 2020. PMID: 32665593 Free PMC article.

5

Proline-rich domain of human ALIX contains multiple TSG101-UEV interaction sites and forms phosphorylation-mediated reversible amyloids.

Elias RD, Ma W, Ghirlando R, Schwieters CD, Reddy VS, Deshmukh L. Elias RD, et al. Proc Natl Acad Sci U S A. 2020 Sep 29;117(39):24274-24284. doi: 10.1073/pnas.2010635117. Epub 2020 Sep 11. Proc Natl Acad Sci U S A. 2020. PMID: 32917811

6

Structural Biology of HIV Integrase Strand Transfer Inhibitors.

Jóźwik IK, Passos DO, Lyumkis D. Jóźwik IK, et al. Trends Pharmacol Sci. 2020 Sep;41(9):611-626. doi: 10.1016/j.tips.2020.06.003. Epub 2020 Jul 3. Trends Pharmacol Sci. 2020. PMID: 32624197 Review.

7

Integrative modeling of the HIV-1 ribonucleoprotein complex.

Goodsell DS, Jewett A, Olson AJ, Forli S. Goodsell DS, et al. PLoS Comput Biol. 2019 Jun 13;15(6):e1007150. doi: 10.1371/journal.pcbi.1007150. eCollection 2019 Jun. PLoS Comput Biol. 2019. PMID: 31194731 Free PMC article.

8

Evolving understanding of HIV-1 reverse transcriptase structure, function, inhibition, and resistance.

Xavier Ruiz F, Arnold E. Xavier Ruiz F, et al. Curr Opin Struct Biol. 2020 Apr;61:113-123. doi: 10.1016/j.sbi.2019.11.011. Epub 2020 Jan 11. Curr Opin Struct Biol. 2020. PMID: 31935541 Review.

9

Intrinsic conformational dynamics of the HIV-1 genomic RNA 5'UTR.

Brigham BS, Kitzrow JP, Reyes JC, Musier-Forsyth K, Munro JB. Brigham BS, et al. Proc Natl Acad Sci U S A. 2019 May 21;116(21):10372-10381. doi: 10.1073/pnas.1902271116. Epub 2019 May 8. Proc Natl Acad Sci U S A. 2019. PMID: 31068467 Free PMC article.

10

Epistasis and entrenchment of drug resistance in HIV-1 subtype B.

Biswas A, Haldane A, Arnold E, Levy RM. Biswas A, et al. Elife. 2019 Oct 8;8:e50524. doi: 10.7554/eLife.50524. Elife. 2019. PMID: 31591964 Free PMC article.

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