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Year Number of Results
2017 1
2018 7
2019 13
2020 6
2021 6
2022 7
2023 3
2024 2

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41 results

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Page 1
Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations.
Varkaris A, Fece de la Cruz F, Martin EE, Norden BL, Chevalier N, Kehlmann AM, Leshchiner I, Barnes H, Ehnstrom S, Stavridi AM, Yuan X, Kim JS, Ellis H, Papatheodoridi A, Gunaydin H, Danysh BP, Parida L, Sanidas I, Ji Y, Lau K, Wulf GM, Bardia A, Spring LM, Isakoff SJ, Lennerz JK, Del Vecchio K, Pierce L, Pazolli E, Getz G, Corcoran RB, Juric D. Varkaris A, et al. Cancer Discov. 2024 Feb 8;14(2):227-239. doi: 10.1158/2159-8290.CD-23-0704. Cancer Discov. 2024. PMID: 37916958 Free PMC article.
Dietary fat and lipid metabolism in the tumor microenvironment.
Goswami S, Zhang Q, Celik CE, Reich EM, Yilmaz ÖH. Goswami S, et al. Biochim Biophys Acta Rev Cancer. 2023 Nov;1878(6):188984. doi: 10.1016/j.bbcan.2023.188984. Epub 2023 Sep 16. Biochim Biophys Acta Rev Cancer. 2023. PMID: 37722512 Free PMC article. Review.
Combined PD-1, BRAF and MEK inhibition in BRAFV600E colorectal cancer: a phase 2 trial.
Tian J, Chen JH, Chao SX, Pelka K, Giannakis M, Hess J, Burke K, Jorgji V, Sindurakar P, Braverman J, Mehta A, Oka T, Huang M, Lieb D, Spurrell M, Allen JN, Abrams TA, Clark JW, Enzinger AC, Enzinger PC, Klempner SJ, McCleary NJ, Meyerhardt JA, Ryan DP, Yurgelun MB, Kanter K, Van Seventer EE, Baiev I, Chi G, Jarnagin J, Bradford WB, Wong E, Michel AG, Fetter IJ, Siravegna G, Gemma AJ, Sharpe A, Demehri S, Leary R, Campbell CD, Yilmaz O, Getz GA, Parikh AR, Hacohen N, Corcoran RB. Tian J, et al. Nat Med. 2023 Feb;29(2):458-466. doi: 10.1038/s41591-022-02181-8. Epub 2023 Jan 26. Nat Med. 2023. PMID: 36702949 Free PMC article. Clinical Trial.
Metabolism and Colorectal Cancer.
Sedlak JC, Yilmaz ÖH, Roper J. Sedlak JC, et al. Annu Rev Pathol. 2023 Jan 24;18:467-492. doi: 10.1146/annurev-pathmechdis-031521-041113. Epub 2022 Nov 2. Annu Rev Pathol. 2023. PMID: 36323004 Free PMC article. Review.
Molecular Pathways and Mechanisms of BRAF in Cancer Therapy.
Poulikakos PI, Sullivan RJ, Yaeger R. Poulikakos PI, et al. Clin Cancer Res. 2022 Nov 1;28(21):4618-4628. doi: 10.1158/1078-0432.CCR-21-2138. Clin Cancer Res. 2022. PMID: 35486097 Free PMC article. Review.
Combined tumor and immune signals from genomes or transcriptomes predict outcomes of checkpoint inhibition in melanoma.
Freeman SS, Sade-Feldman M, Kim J, Stewart C, Gonye ALK, Ravi A, Arniella MB, Gushterova I, LaSalle TJ, Blaum EM, Yizhak K, Frederick DT, Sharova T, Leshchiner I, Elagina L, Spiro OG, Livitz D, Rosebrock D, Aguet F, Carrot-Zhang J, Ha G, Lin Z, Chen JH, Barzily-Rokni M, Hammond MR, Vitzthum von Eckstaedt HC, Blackmon SM, Jiao YJ, Gabriel S, Lawrence DP, Duncan LM, Stemmer-Rachamimov AO, Wargo JA, Flaherty KT, Sullivan RJ, Boland GM, Meyerson M, Getz G, Hacohen N. Freeman SS, et al. Cell Rep Med. 2022 Feb 15;3(2):100500. doi: 10.1016/j.xcrm.2021.100500. eCollection 2022 Feb 15. Cell Rep Med. 2022. PMID: 35243413 Free PMC article.
Understanding Drug Sensitivity and Tackling Resistance in Cancer.
Tyner JW, Haderk F, Kumaraswamy A, Baughn LB, Van Ness B, Liu S, Marathe H, Alumkal JJ, Bivona TG, Chan KS, Druker BJ, Hutson AD, Nelson PS, Sawyers CL, Willey CD. Tyner JW, et al. Cancer Res. 2022 Apr 15;82(8):1448-1460. doi: 10.1158/0008-5472.CAN-21-3695. Cancer Res. 2022. PMID: 35195258 Free PMC article.
41 results