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2015 15
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Page 1
Initiation of Antiretroviral Therapy in Early Asymptomatic HIV Infection.
INSIGHT START Study Group; Lundgren JD, Babiker AG, Gordin F, Emery S, Grund B, Sharma S, Avihingsanon A, Cooper DA, Fätkenheuer G, Llibre JM, Molina JM, Munderi P, Schechter M, Wood R, Klingman KL, Collins S, Lane HC, Phillips AN, Neaton JD. INSIGHT START Study Group, et al. N Engl J Med. 2015 Aug 27;373(9):795-807. doi: 10.1056/NEJMoa1506816. Epub 2015 Jul 20. N Engl J Med. 2015. PMID: 26192873 Free PMC article. Clinical Trial.
Why START? Reflections that led to the conduct of this large long-term strategic HIV trial.
INSIGHT Strategic Timing of AntiRetroviral Treatment (START) Study Group; Lundgren J, Babiker A, Gordin F, Emery S, Fätkenheuer G, Molina JM, Wood R, Neaton JD. INSIGHT Strategic Timing of AntiRetroviral Treatment (START) Study Group, et al. HIV Med. 2015 Apr;16 Suppl 1(0 1):1-9. doi: 10.1111/hiv.12227. HIV Med. 2015. PMID: 25711317 Free PMC article. No abstract available.
Human Immunotypes Impose Selection on Viral Genotypes Through Viral Epitope Specificity.
Gabrielaite M, Bennedbæk M, Zucco AG, Ekenberg C, Murray DD, Kan VL, Touloumi G, Vandekerckhove L, Turner D, Neaton J, Lane HC, Safo S, Arenas-Pinto A, Polizzotto MN, Günthard HF, Lundgren JD, Marvig RL. Gabrielaite M, et al. J Infect Dis. 2021 Dec 15;224(12):2053-2063. doi: 10.1093/infdis/jiab253. J Infect Dis. 2021. PMID: 33974707 Free PMC article.
DNA methylation is associated with airflow obstruction in patients living with HIV.
Hernandez Cordero AI, Yang CX, Obeidat M, Yang J, MacIsaac J, McEwen L, Lin D, Kobor M, Novak R, Hudson F, Klinker H, Dharan N, Man SP, Sin DD, Kunisaki K, Leung J; INSIGHT START Pulmonary and Genomic Substudy Groups. Hernandez Cordero AI, et al. Thorax. 2021 May;76(5):448-455. doi: 10.1136/thoraxjnl-2020-215866. Epub 2020 Dec 18. Thorax. 2021. PMID: 33443234 Free PMC article. Clinical Trial.
Faster lung function decline in people living with HIV despite adequate treatment: a longitudinal matched cohort study.
Thudium RF, Ronit A, Afzal S, Çolak Y, Forman JL, Mendo F, Chen F, Estrada V, Kumarasamy N, Nordestgaard BG, Lundgren J, Vestbo J, Kunisaki KM, Nielsen SD; COCOMO, INSIGHT START Pulmonary Substudy and CGPS Study Groups. Thudium RF, et al. Thorax. 2023 Jun;78(6):535-542. doi: 10.1136/thorax-2022-218910. Epub 2023 Jan 13. Thorax. 2023. PMID: 36639241
Deep-sequencing of viral genomes from a large and diverse cohort of treatment-naive HIV-infected persons shows associations between intrahost genetic diversity and viral load.
Gabrielaite M, Bennedbæk M, Rasmussen MS, Kan V, Furrer H, Flisiak R, Losso M, Lundgren JD; INSIGHT START Study Group; Marvig RL. Gabrielaite M, et al. PLoS Comput Biol. 2023 Jan 3;19(1):e1010756. doi: 10.1371/journal.pcbi.1010756. eCollection 2023 Jan. PLoS Comput Biol. 2023. PMID: 36595537 Free PMC article.
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