Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 8
2005 14
2006 29
2007 48
2008 46
2009 43
2010 31
2011 42
2012 47
2013 42
2014 53
2015 53
2016 48
2017 47
2018 42
2019 31
2020 28
2021 22
Text availability
Article attribute
Article type
Publication date

Search Results

562 results
Results by year
Filters applied: . Clear all
Page 1
URB597 protects against NLRP3 inflammasome activation by inhibiting autophagy dysfunction in a rat model of chronic cerebral hypoperfusion.
Su SH, Wu YF, Lin Q, Wang DP, Hai J. Su SH, et al. J Neuroinflammation. 2019 Dec 9;16(1):260. doi: 10.1186/s12974-019-1668-0. J Neuroinflammation. 2019. PMID: 31815636 Free PMC article.
BACKGROUND: Previous studies reported that URB597 (URB) had therapeutic potential for treating chronic cerebral hypoperfusion (CCH)-induced neuroinflammation and autophagy dysfunction. ...METHODS: The CCH rat model was established by bilateral common carotid artery occlusi …
BACKGROUND: Previous studies reported that URB597 (URB) had therapeutic potential for treating chronic cerebral hypoperfusion (CCH)-i …
The cannabinoid system and pain.
Woodhams SG, Chapman V, Finn DP, Hohmann AG, Neugebauer V. Woodhams SG, et al. Neuropharmacology. 2017 Sep 15;124:105-120. doi: 10.1016/j.neuropharm.2017.06.015. Epub 2017 Jun 15. Neuropharmacology. 2017. PMID: 28625720 Free PMC article. Review.
Pharmacological enhancement of endocannabinoid activity (via blockade of EC metabolism or allosteric modulation of CB(1)receptors); 2. The EC System and stress-induced modulation of pain; and 3. The EC system & medial prefrontal cortex (mPFC) dysfunction in pain states …
Pharmacological enhancement of endocannabinoid activity (via blockade of EC metabolism or allosteric modulation of CB(1)receptors); 2. The E …
The FAAH Inhibitor URB597 Modulates Lipid Mediators in the Brain of Rats with Spontaneous Hypertension.
Biernacki M, Baranowska-Kuczko M, Niklińska GN, Skrzydlewska E. Biernacki M, et al. Biomolecules. 2020 Jul 10;10(7):1022. doi: 10.3390/biom10071022. Biomolecules. 2020. PMID: 32664225 Free PMC article.
The present study tested whether chronic administration of the fatty acid amide hydrolase (FAAH) inhibitor [3-(3-carbamoylphenyl) phenyl]N-cyclohexylcarbamate (URB597) to rats with primary hypertension (SHR) can modify redox balance and consequently br …
The present study tested whether chronic administration of the fatty acid amide hydrolase (FAAH) inhibitor [3-(3-carbam …
The fatty-acid amide hydrolase inhibitor URB597 inhibits MICA/B shedding.
Sekiba K, Otsuka M, Seimiya T, Tanaka E, Funato K, Miyakawa Y, Koike K. Sekiba K, et al. Sci Rep. 2020 Sep 23;10(1):15556. doi: 10.1038/s41598-020-72688-y. Sci Rep. 2020. PMID: 32968163 Free PMC article.
Here, by screening a protease inhibitor library, we found that the fatty-acid amide hydrolase (FAAH) inhibitor, URB597, suppresses the shedding of MICA/B. ...The effect was indirect, being mediated by increased expression of tissue inhibitor of metalloproteinases …
Here, by screening a protease inhibitor library, we found that the fatty-acid amide hydrolase (FAAH) inhibitor, URB597, suppre …
URB597 ameliorates the deleterious effects induced by binge alcohol consumption in adolescent rats.
Bellozi PMQ, Pelição R, Santos MC, Lima IVA, Saliba SW, Vieira ÉLM, Campos AC, Teixeira AL, de Oliveira ACP, Nakamura-Palacios EM, Rodrigues LCM. Bellozi PMQ, et al. Neurosci Lett. 2019 Oct 15;711:134408. doi: 10.1016/j.neulet.2019.134408. Epub 2019 Jul 30. Neurosci Lett. 2019. PMID: 31374324 Free article.
The animals received intraperitoneal injections of URB597 (0.3 mg/Kg) or vehicle followed by the oral administration of ethanol (3 or 6 g/Kg) or distilled water for 3 consecutive days in one week (acute binging) or over 4 weeks (chronic binging). The g …
The animals received intraperitoneal injections of URB597 (0.3 mg/Kg) or vehicle followed by the oral administration of ethano …
URB597 abrogates anxiogenic and depressive behaviors in the methamphetamine-withdrawal mice: Role of the cannabinoid receptor type 1, cannabinoid receptor type 2, and transient receptor potential vanilloid 1 channels.
Ebrahimi-Ghiri M, Khakpai F, Zarrindast MR. Ebrahimi-Ghiri M, et al. J Psychopharmacol. 2021 Jul;35(7):875-884. doi: 10.1177/0269881120965934. Epub 2020 Nov 6. J Psychopharmacol. 2021. PMID: 33155516
RESULTS: We found that methamphetamine (30 mg/kg, intraperitoneal) evoked depressive- and anxiogenic-like effects at 3 days post-administration. Injection of URB597 (5-10 ng/mouse, intracerebroventricular), 10 min before the test, prevented the emotional deficits in …
RESULTS: We found that methamphetamine (30 mg/kg, intraperitoneal) evoked depressive- and anxiogenic-like effects at 3 days post-admi …
Antidepressant-like effects of URB597 and JZL184 in male and female rats exposed to early life stress.
Alteba S, Mizrachi Zer-Aviv T, Tenenhaus A, Ben David G, Adelman J, Hillard CJ, Doron R, Akirav I. Alteba S, et al. Eur Neuropsychopharmacol. 2020 Oct;39:70-86. doi: 10.1016/j.euroneuro.2020.08.005. Epub 2020 Sep 2. Eur Neuropsychopharmacol. 2020. PMID: 32891517
Male and female rats were exposed to ELS during post-natal days (P) 7-14, injected with the fatty acid amide hydrolase (FAAH) inhibitor URB597 or the monoacylglycerol lipase (MAGL) inhibitor JZL184 for 2 weeks during late-adolescence (P45-60). ...
Male and female rats were exposed to ELS during post-natal days (P) 7-14, injected with the fatty acid amide hydrolase (FAAH) inhibit …
Chronic treatment with URB597 ameliorates post-stress symptoms in a rat model of PTSD.
Fidelman S, Mizrachi Zer-Aviv T, Lange R, Hillard CJ, Akirav I. Fidelman S, et al. Eur Neuropsychopharmacol. 2018 May;28(5):630-642. doi: 10.1016/j.euroneuro.2018.02.004. Epub 2018 Mar 5. Eur Neuropsychopharmacol. 2018. PMID: 29519609
Activating the endocannabinoid system has become a major focus in the search for novel therapeutics for anxiety and deficits in fear extinction, two defining features of PTSD. We examined whether chronic treatment with the fatty acid amide hydrolase (FAAH) inhibitor URB
Activating the endocannabinoid system has become a major focus in the search for novel therapeutics for anxiety and deficits in fear extinct …
URB597 Prevents the Short-Term Excitotoxic Cell Damage in Rat Cortical Slices: Role of Cannabinoid 1 Receptors.
Chavira-Ramos K, Orozco-Morales M, Karasu Ç, Tinkov AA, Aschner M, Santamaría A, Colín-González AL. Chavira-Ramos K, et al. Neurotox Res. 2021 Apr;39(2):146-155. doi: 10.1007/s12640-020-00301-1. Epub 2020 Nov 3. Neurotox Res. 2021. PMID: 33141426
Endocannabinoid-based therapies constitute an emerging tool for the potential treatment of neurodegenerative disorders, requiring characterization at the experimental level. The effects of URB597, an inhibitor of the fatty acid amide hydrolase (FAAH), were tested ag …
Endocannabinoid-based therapies constitute an emerging tool for the potential treatment of neurodegenerative disorders, requiring characteri …
The Effect of Long-Term Administration of Fatty Acid Amide Hydrolase Inhibitor URB597 on Oxidative Metabolism in the Heart of Rats with Primary and Secondary Hypertension.
Biernacki M, Łuczaj W, Jarocka-Karpowicz I, Ambrożewicz E, Toczek M, Skrzydlewska E. Biernacki M, et al. Molecules. 2018 Sep 14;23(9):2350. doi: 10.3390/molecules23092350. Molecules. 2018. PMID: 30223427 Free PMC article.
Fatty acid amide hydrolase (FAAH) inhibitor [3-(3-carbamoylphenyl)phenyl] N-cyclohexylcarbamate (URB597) may influence redox balance and blood pressure through the modulation of endocannabinoids levels. ...Furthermore, decreased expression of pro-apopt …
Fatty acid amide hydrolase (FAAH) inhibitor [3-(3-carbamoylphenyl)phenyl] N-cyclohexylcarbamate (URB597) may inf …
562 results
You have reached the last page of results. A maximum of 10,000 results are available.
Jump to page