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A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway.
Morimitsu Y, Nakagawa Y, Hayashi K, Fujii H, Kumagai T, Nakamura Y, Osawa T, Horio F, Itoh K, Iida K, Yamamoto M, Uchida K. Morimitsu Y, et al. Among authors: uchida k. J Biol Chem. 2002 Feb 1;277(5):3456-63. doi: 10.1074/jbc.M110244200. Epub 2001 Nov 12. J Biol Chem. 2002. PMID: 11706044 Free article.
., Naito, Y., Torii, Y., Kumagai, T., Osawa, T., Ohigashi, H., Satoh, K., Imagawa, M., and Uchida, K. (2000) J. Biol. Chem. 275, 11291-11299.) ...
., Naito, Y., Torii, Y., Kumagai, T., Osawa, T., Ohigashi, H., Satoh, K., Imagawa, M., and Uchida, K. (2000) J. Biol. C …
Thiolation of protein-bound carcinogenic aldehyde. An electrophilic acrolein-lysine adduct that covalently binds to thiols.
Furuhata A, Nakamura M, Osawa T, Uchida K. Furuhata A, et al. Among authors: uchida k. J Biol Chem. 2002 Aug 2;277(31):27919-26. doi: 10.1074/jbc.M202794200. Epub 2002 May 24. J Biol Chem. 2002. PMID: 12032148 Free article.
Acrolein, a representative carcinogenic aldehyde that could be ubiquitously generated in biological systems under oxidative stress, shows facile reactivity with the epsilon-amino group of lysine to form N(epsilon)-(3-formyl-3,4-dehydropiperidino)lysine (FDP-lysine) as the major p …
Acrolein, a representative carcinogenic aldehyde that could be ubiquitously generated in biological systems under oxidative stress, shows fa …
5,591 results