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Molecular characterization of N-acylethanolamine-hydrolyzing acid amidase, a novel member of the choloylglycine hydrolase family with structural and functional similarity to acid ceramidase.
Tsuboi K, Sun YX, Okamoto Y, Araki N, Tonai T, Ueda N. Tsuboi K, et al. Among authors: ueda n. J Biol Chem. 2005 Mar 25;280(12):11082-92. doi: 10.1074/jbc.M413473200. Epub 2005 Jan 17. J Biol Chem. 2005. PMID: 15655246 Free article.
Moreover, we found another amidohydrolase catalyzing the same reaction only at acidic pH, and we purified it from rat lung (Ueda, N., Yamanaka, K., and Yamamoto, S. (2001) J. Biol. Chem. 276, 35552-35557). ...The recombinant human NAAA overexpressed in HEK293 cells …
Moreover, we found another amidohydrolase catalyzing the same reaction only at acidic pH, and we purified it from rat lung (Ueda, …
Involvement of N-acylethanolamine-hydrolyzing acid amidase in the degradation of anandamide and other N-acylethanolamines in macrophages.
Sun YX, Tsuboi K, Zhao LY, Okamoto Y, Lambert DM, Ueda N. Sun YX, et al. Among authors: ueda n. Biochim Biophys Acta. 2005 Oct 1;1736(3):211-20. doi: 10.1016/j.bbalip.2005.08.010. Epub 2005 Aug 29. Biochim Biophys Acta. 2005. PMID: 16154384 Free article.
In addition, we recently cloned an isozyme termed "N-acylethanolamine-hydrolyzing acid amidase (NAAA)", which is active only at acidic pH [Tsuboi, Sun, Okamoto, Araki, Tonai, Ueda, J. ...The homogenates of RAW264.7 cells showed both the NAAA and FAAH activities whic …
In addition, we recently cloned an isozyme termed "N-acylethanolamine-hydrolyzing acid amidase (NAAA)", which is active only at acidi …
Predominant expression of lysosomal N-acylethanolamine-hydrolyzing acid amidase in macrophages revealed by immunochemical studies.
Tsuboi K, Zhao LY, Okamoto Y, Araki N, Ueno M, Sakamoto H, Ueda N. Tsuboi K, et al. Among authors: ueda n. Biochim Biophys Acta. 2007 May;1771(5):623-32. doi: 10.1016/j.bbalip.2007.03.005. Epub 2007 Mar 24. Biochim Biophys Acta. 2007. PMID: 17462942
Bioactive N-acylethanolamines, including anandamide (an endocannabinoid), N-palmitoylethanolamine (an anti-inflammatory substance), and N-oleoylethanolamine (an anorexic substance) are enzymatically hydrolyzed to fatty acids and ethanolamine. ...-X. Sun, Y. O …
Bioactive N-acylethanolamines, including anandamide (an endocannabinoid), N-palmitoylethanolamine (an anti-inflammatory substa …
1,491 results