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α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson's disease model.
Taguchi T, Ikuno M, Hondo M, Parajuli LK, Taguchi K, Ueda J, Sawamura M, Okuda S, Nakanishi E, Hara J, Uemura N, Hatanaka Y, Ayaki T, Matsuzawa S, Tanaka M, El-Agnaf OMA, Koike M, Yanagisawa M, Uemura MT, Yamakado H, Takahashi R. Taguchi T, et al. Among authors: uemura n, uemura mt. Brain. 2020 Jan 1;143(1):249-265. doi: 10.1093/brain/awz380. Brain. 2020. PMID: 31816026
PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates.
Matsui H, Gavinio R, Asano T, Uemura N, Ito H, Taniguchi Y, Kobayashi Y, Maki T, Shen J, Takeda S, Uemura K, Yamakado H, Takahashi R. Matsui H, et al. Among authors: uemura n, uemura k. Hum Mol Genet. 2013 Jun 15;22(12):2423-34. doi: 10.1093/hmg/ddt095. Epub 2013 Feb 27. Hum Mol Genet. 2013. PMID: 23449626 Free PMC article.
ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons.
Matsui H, Sato F, Sato S, Koike M, Taruno Y, Saiki S, Funayama M, Ito H, Taniguchi Y, Uemura N, Toyoda A, Sakaki Y, Takeda S, Uchiyama Y, Hattori N, Takahashi R. Matsui H, et al. Among authors: uemura n. FEBS Lett. 2013 May 2;587(9):1316-25. doi: 10.1016/j.febslet.2013.02.046. Epub 2013 Mar 13. FEBS Lett. 2013. PMID: 23499937 Free article.
Innate immunity regulates α-synuclein clearance.
Sawamura M, Uemura N, Takahashi R. Sawamura M, et al. Among authors: uemura n. Mov Disord. 2016 May;31(5):638. doi: 10.1002/mds.26571. Epub 2016 Mar 4. Mov Disord. 2016. PMID: 26946483 Review. No abstract available.
Pathological Endogenous α-Synuclein Accumulation in Oligodendrocyte Precursor Cells Potentially Induces Inclusions in Multiple System Atrophy.
Kaji S, Maki T, Kinoshita H, Uemura N, Ayaki T, Kawamoto Y, Furuta T, Urushitani M, Hasegawa M, Kinoshita Y, Ono Y, Mao X, Quach TH, Iwai K, Dawson VL, Dawson TM, Takahashi R. Kaji S, et al. Among authors: uemura n. Stem Cell Reports. 2018 Feb 13;10(2):356-365. doi: 10.1016/j.stemcr.2017.12.001. Epub 2018 Jan 11. Stem Cell Reports. 2018. PMID: 29337114 Free PMC article.
582 results