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Mechanism of HDL lowering in insulin resistant states.
Lewis GF, Rashid S, Uffelman KD, Lamarche B. Lewis GF, et al. Among authors: uffelman kd. Adv Exp Med Biol. 2001;498:273-7. doi: 10.1007/978-1-4615-1321-6_34. Adv Exp Med Biol. 2001. PMID: 11900379 Review. No abstract available.
Enhancement of muscle glucose uptake by the vasopeptidase inhibitor, omapatrilat, is independent of insulin signaling and the AMP kinase pathway.
Wong V, Szeto L, Uffelman K, Fantus IG, Lewis GF. Wong V, et al. J Endocrinol. 2006 Aug;190(2):441-50. doi: 10.1677/joe.1.06396. J Endocrinol. 2006. PMID: 16899577
Atorvastatin induces insulin sensitization in Zucker lean and fatty rats.
Wong V, Stavar L, Szeto L, Uffelman K, Wang CH, Fantus IG, Lewis GF. Wong V, et al. Atherosclerosis. 2006 Feb;184(2):348-55. doi: 10.1016/j.atherosclerosis.2005.05.009. Epub 2005 Jul 5. Atherosclerosis. 2006. PMID: 15998521
Hepatic lipase mRNA, protein, and plasma enzyme activity is increased in the insulin-resistant, fructose-fed Syrian golden hamster and is partially normalized by the insulin sensitizer rosiglitazone.
Lewis GF, Murdoch S, Uffelman K, Naples M, Szeto L, Albers A, Adeli K, Brunzell JD. Lewis GF, et al. Diabetes. 2004 Nov;53(11):2893-900. doi: 10.2337/diabetes.53.11.2893. Diabetes. 2004. PMID: 15504970
Intestinal lipoprotein overproduction, a newly recognized component of insulin resistance, is ameliorated by the insulin sensitizer rosiglitazone: studies in the fructose-fed Syrian golden hamster.
Lewis GF, Uffelman K, Naples M, Szeto L, Haidari M, Adeli K. Lewis GF, et al. Endocrinology. 2005 Jan;146(1):247-55. doi: 10.1210/en.2004-1143. Epub 2004 Oct 14. Endocrinology. 2005. PMID: 15486228
Rosiglitazone improves intestinal lipoprotein overproduction in the fat-fed Syrian Golden hamster, an animal model of nutritionally-induced insulin resistance.
Leung N, Naples M, Uffelman K, Szeto L, Adeli K, Lewis GF. Leung N, et al. Atherosclerosis. 2004 Jun;174(2):235-41. doi: 10.1016/j.atherosclerosis.2004.02.005. Atherosclerosis. 2004. PMID: 15136053
Intestinal lipoprotein production is stimulated by an acute elevation of plasma free fatty acids in the fasting state: studies in insulin-resistant and insulin-sensitized Syrian golden hamsters.
Lewis GF, Naples M, Uffelman K, Leung N, Szeto L, Adeli K. Lewis GF, et al. Endocrinology. 2004 Nov;145(11):5006-12. doi: 10.1210/en.2003-1559. Epub 2004 Jul 22. Endocrinology. 2004. PMID: 15271878
Hyperinsulinemia is associated with increased production rate of intestinal apolipoprotein B-48-containing lipoproteins in humans.
Duez H, Lamarche B, Uffelman KD, Valero R, Cohn JS, Lewis GF. Duez H, et al. Among authors: uffelman kd. Arterioscler Thromb Vasc Biol. 2006 Jun;26(6):1357-63. doi: 10.1161/01.ATV.0000222015.76038.14. Epub 2006 Apr 13. Arterioscler Thromb Vasc Biol. 2006. PMID: 16614317
Dissociation between the insulin-sensitizing effect of rosiglitazone and its effect on hepatic and intestinal lipoprotein production.
Duez H, Lamarche B, Uffelman KD, Valéro R, Szeto L, Lemieux S, Cohn JS, Lewis GF. Duez H, et al. Among authors: uffelman kd. J Clin Endocrinol Metab. 2008 May;93(5):1722-9. doi: 10.1210/jc.2007-2110. Epub 2008 Feb 19. J Clin Endocrinol Metab. 2008. PMID: 18285418 Clinical Trial.
Expression of human hepatic lipase in the rabbit model preferentially enhances the clearance of triglyceride-enriched versus native high-density lipoprotein apolipoprotein A-I.
Rashid S, Trinh DK, Uffelman KD, Cohn JS, Rader DJ, Lewis GF. Rashid S, et al. Among authors: uffelman kd. Circulation. 2003 Jun 24;107(24):3066-72. doi: 10.1161/01.CIR.0000070947.64595.47. Epub 2003 Jun 9. Circulation. 2003. PMID: 12796142
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