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Choline increases acetylcholine release and protects against the stimulation-induced decrease in phosphatide levels within membranes of rat corpus striatum.
Ulus IH, Wurtman RJ, Mauron C, Blusztajn JK. Ulus IH, et al. Brain Res. 1989 Apr 10;484(1-2):217-27. doi: 10.1016/0006-8993(89)90364-8. Brain Res. 1989. PMID: 2713682
Stimulation of CDP-choline synthesis by uridine or cytidine in PC12 rat pheochromocytoma cells.
Richardson UI, Watkins CJ, Pierre C, Ulus IH, Wurtman RJ. Richardson UI, et al. Among authors: ulus ih. Brain Res. 2003 May 9;971(2):161-7. doi: 10.1016/s0006-8993(03)02333-3. Brain Res. 2003. PMID: 12706232
Regional distribution of neurotransmitter-synthesizing enzymes and substance P within the rat corpus striatum.
Scally MC, Ulus IH, Wurtman RJ, Pettibone DJ. Scally MC, et al. Among authors: ulus ih. Brain Res. 1978 Mar 31;143(3):556-60. doi: 10.1016/0006-8993(78)90367-0. Brain Res. 1978. PMID: 25694 No abstract available.
Choline increases acetylcholine release.
Ulus IH, Wurtman RJ. Ulus IH, et al. Lancet. 1987 Mar 14;1(8533):624. doi: 10.1016/s0140-6736(87)90258-3. Lancet. 1987. PMID: 2881154 No abstract available.
Caffeine potentiates the enhancement by choline of striatal acetylcholine release.
Johnson DA, Ulus IH, Wurtman RJ. Johnson DA, et al. Among authors: ulus ih. Life Sci. 1992;51(20):1597-601. doi: 10.1016/0024-3205(92)90622-v. Life Sci. 1992. PMID: 1435067
N-methyl-D-aspartate increases acetylcholine release from rat striatum and cortex: its effect is augmented by choline.
Ulus IH, Buyukuysal RL, Wurtman RJ. Ulus IH, et al. J Pharmacol Exp Ther. 1992 Jun;261(3):1122-8. J Pharmacol Exp Ther. 1992. PMID: 1602377
Nutritional modifiers of aging brain function: use of uridine and other phosphatide precursors to increase formation of brain synapses.
Wurtman RJ, Cansev M, Sakamoto T, Ulus I. Wurtman RJ, et al. Nutr Rev. 2010 Dec;68 Suppl 2(Suppl 2):S88-101. doi: 10.1111/j.1753-4887.2010.00344.x. Nutr Rev. 2010. PMID: 21091953 Free PMC article. Review.
Synapse formation is enhanced by oral administration of uridine and DHA, the circulating precursors of brain phosphatides.
Wurtman RJ, Cansev M, Ulus IH. Wurtman RJ, et al. Among authors: ulus ih. J Nutr Health Aging. 2009 Mar;13(3):189-97. doi: 10.1007/s12603-009-0056-3. J Nutr Health Aging. 2009. PMID: 19262950 Review.
Metabotropic glutamate receptor agonists increase release of soluble amyloid precursor protein derivatives from rat brain cortical and hippocampal slices.
Ulus IH, Wurtman RJ. Ulus IH, et al. J Pharmacol Exp Ther. 1997 Apr;281(1):149-54. J Pharmacol Exp Ther. 1997. PMID: 9103492
Choline potentiates the trans-synaptic induction of adrenal tyrosine hydroxylase by reserpine, probably by enhancing the release of acetylcholine.
Ulus IH, Scally MC, Wurtman RJ. Ulus IH, et al. Life Sci. 1977 Jul 1;21(1):145-8. doi: 10.1016/0024-3205(77)90435-0. Life Sci. 1977. PMID: 18644 No abstract available.
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