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S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway.
Pende M, Um SH, Mieulet V, Sticker M, Goss VL, Mestan J, Mueller M, Fumagalli S, Kozma SC, Thomas G. Pende M, et al. Among authors: um sh. Mol Cell Biol. 2004 Apr;24(8):3112-24. doi: 10.1128/MCB.24.8.3112-3124.2004. Mol Cell Biol. 2004. PMID: 15060135 Free PMC article.
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