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12 results
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Effect of crocetin from Gardenia jasminoides Ellis on sleep: a pilot study.
Kuratsune H, Umigai N, Takeno R, Kajimoto Y, Nakano T. Kuratsune H, et al. Among authors: umigai n. Phytomedicine. 2010 Sep;17(11):840-3. doi: 10.1016/j.phymed.2010.03.025. Phytomedicine. 2010. PMID: 20537515 Clinical Trial.
Safety Evaluation and Plasma Carotenoid Accumulation in Healthy Adult Subjects after 12 Weeks of Paprika Oleoresin Supplementation.
Umigai N, Murakami K, Shimizu R, Takeda R, Azuma T. Umigai N, et al. J Oleo Sci. 2018 Feb 1;67(2):225-234. doi: 10.5650/jos.ess17155. Epub 2018 Jan 23. J Oleo Sci. 2018. PMID: 29367485 Free article.
Effect of crocetin on quality of sleep: A randomized, double-blind, placebo-controlled, crossover study.
Umigai N, Takeda R, Mori A. Umigai N, et al. Complement Ther Med. 2018 Dec;41:47-51. doi: 10.1016/j.ctim.2018.09.003. Epub 2018 Sep 8. Complement Ther Med. 2018. PMID: 30477864 Clinical Trial.
The pharmacokinetic profile of crocetin in healthy adult human volunteers after a single oral administration.
Umigai N, Murakami K, Ulit MV, Antonio LS, Shirotori M, Morikawa H, Nakano T. Umigai N, et al. Phytomedicine. 2011 May 15;18(7):575-8. doi: 10.1016/j.phymed.2010.10.019. Epub 2010 Nov 26. Phytomedicine. 2011. PMID: 21112749
Crocetin, a carotenoid derivative, inhibits retinal ischemic damage in mice.
Ishizuka F, Shimazawa M, Umigai N, Ogishima H, Nakamura S, Tsuruma K, Hara H. Ishizuka F, et al. Among authors: umigai n. Eur J Pharmacol. 2013 Mar 5;703(1-3):1-10. doi: 10.1016/j.ejphar.2013.02.007. Epub 2013 Feb 18. Eur J Pharmacol. 2013. PMID: 23428630
Crocetin prevents retinal degeneration induced by oxidative and endoplasmic reticulum stresses via inhibition of caspase activity.
Yamauchi M, Tsuruma K, Imai S, Nakanishi T, Umigai N, Shimazawa M, Hara H. Yamauchi M, et al. Among authors: umigai n. Eur J Pharmacol. 2011 Jan 10;650(1):110-9. doi: 10.1016/j.ejphar.2010.09.081. Epub 2010 Oct 14. Eur J Pharmacol. 2011. PMID: 20951131
Crocetin, a carotenoid derivative, inhibits VEGF-induced angiogenesis via suppression of p38 phosphorylation.
Umigai N, Tanaka J, Tsuruma K, Shimazawa M, Hara H. Umigai N, et al. Curr Neurovasc Res. 2012 May;9(2):102-9. doi: 10.2174/156720212800410830. Curr Neurovasc Res. 2012. PMID: 22475394
Oral administration of crocetin prevents inner retinal damage induced by N-methyl-D-aspartate in mice.
Ohno Y, Nakanishi T, Umigai N, Tsuruma K, Shimazawa M, Hara H. Ohno Y, et al. Among authors: umigai n. Eur J Pharmacol. 2012 Sep 5;690(1-3):84-9. doi: 10.1016/j.ejphar.2012.06.035. Epub 2012 Jul 1. Eur J Pharmacol. 2012. PMID: 22760072
Crocetin reduces the oxidative stress induced reactive oxygen species in the stroke-prone spontaneously hypertensive rats (SHRSPs) brain.
Yoshino F, Yoshida A, Umigai N, Kubo K, Lee MC. Yoshino F, et al. Among authors: umigai n. J Clin Biochem Nutr. 2011 Nov;49(3):182-7. doi: 10.3164/jcbn.11-01. Epub 2011 Oct 29. J Clin Biochem Nutr. 2011. PMID: 22128217 Free PMC article.
Crocetin protects ultraviolet A-induced oxidative stress and cell death in skin in vitro and in vivo.
Ohba T, Ishisaka M, Tsujii S, Tsuruma K, Shimazawa M, Kubo K, Umigai N, Iwawaki T, Hara H. Ohba T, et al. Among authors: umigai n. Eur J Pharmacol. 2016 Oct 15;789:244-253. doi: 10.1016/j.ejphar.2016.07.036. Epub 2016 Jul 21. Eur J Pharmacol. 2016. PMID: 27452919
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