Unadkat JD - Search Results

1

Enzymes in addition to CYP3A4 and 3A5 mediate N-demethylation of dextromethorphan in human liver microsomes.

Wang Y, Unadkat JD. Wang Y, et al. Among authors: unadkat jd. Biopharm Drug Dispos. 1999 Oct;20(7):341-6. doi: 10.1002/(sici)1099-081x(199910)20:7<341::aid-bdd195>3.0.co;2-f. Biopharm Drug Dispos. 1999. PMID: 10760842

2

Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo.

Mitra AK, Thummel KE, Kalhorn TF, Kharasch ED, Unadkat JD, Slattery JT. Mitra AK, et al. Among authors: unadkat jd. Clin Pharmacol Ther. 1995 Nov;58(5):556-66. doi: 10.1016/0009-9236(95)90176-0. Clin Pharmacol Ther. 1995. PMID: 7586950 Clinical Trial.

3

Dapsone acetylation by human liver arylamine N-acetyltransferases and interaction with antiopportunistic infection drugs.

Palamanda JR, Hickman D, Ward A, Sim E, Romkes-Sparks M, Unadkat JD. Palamanda JR, et al. Among authors: unadkat jd. Drug Metab Dispos. 1995 Apr;23(4):473-7. Drug Metab Dispos. 1995. PMID: 7600914

4

Disposition of drugs in cystic fibrosis. VI. In vivo activity of cytochrome P450 isoforms involved in the metabolism of (R)-warfarin (including P450 3A4) is not enhanced in cystic fibrosis.

Wang JP, Unadkat JD, McNamara S, O'Sullivan TA, Smith AL, Trager WF, Ramsey B. Wang JP, et al. Among authors: unadkat jd. Clin Pharmacol Ther. 1994 May;55(5):528-34. doi: 10.1038/clpt.1994.66. Clin Pharmacol Ther. 1994. PMID: 8181197

5

Disposition of drugs in cystic fibrosis. V. In vivo CYP2C9 activity as probed by (S)-warfarin is not enhanced in cystic fibrosis.

O'Sullivan TA, Wang JP, Unadkat JD, al-Habet SM, Trager WF, Smith AL, McNamara S, Aitken ML. O'Sullivan TA, et al. Among authors: unadkat jd. Clin Pharmacol Ther. 1993 Sep;54(3):323-8. doi: 10.1038/clpt.1993.154. Clin Pharmacol Ther. 1993. PMID: 8375128

6

Inhibition of sulfamethoxazole hydroxylamine formation by fluconazole in human liver microsomes and healthy volunteers.

Mitra AK, Thummel KE, Kalhorn TF, Kharasch ED, Unadkat JD, Slattery JT. Mitra AK, et al. Among authors: unadkat jd. Clin Pharmacol Ther. 1996 Mar;59(3):332-40. doi: 10.1016/S0009-9236(96)80011-7. Clin Pharmacol Ther. 1996. PMID: 8653996 Clinical Trial.

7

Evaluation of the selectivity of In vitro probes and suitability of organic solvents for the measurement of human cytochrome P450 monooxygenase activities.

Hickman D, Wang JP, Wang Y, Unadkat JD. Hickman D, et al. Among authors: unadkat jd. Drug Metab Dispos. 1998 Mar;26(3):207-15. Drug Metab Dispos. 1998. PMID: 9492382

8

Expression of arylamine N-acetyltransferase in human intestine.

Hickman D, Pope J, Patil SD, Fakis G, Smelt V, Stanley LA, Payton M, Unadkat JD, Sim E. Hickman D, et al. Among authors: unadkat jd. Gut. 1998 Mar;42(3):402-9. doi: 10.1136/gut.42.3.402. Gut. 1998. PMID: 9577349 Free PMC article.

9

In vitro models to predict the in vivo mechanism, rate, and extent of placental transfer of dideoxynucleoside drugs against human immunodeficiency virus.

Tuntland T, Odinecs A, Pereira CM, Nosbisch C, Unadkat JD. Tuntland T, et al. Among authors: unadkat jd. Am J Obstet Gynecol. 1999 Jan;180(1 Pt 1):198-206. doi: 10.1016/s0002-9378(99)70175-4. Am J Obstet Gynecol. 1999. PMID: 9914604

10

Human intestinal es nucleoside transporter: molecular characterization and nucleoside inhibitory profiles.

Lum PY, Ngo LY, Bakken AH, Unadkat JD. Lum PY, et al. Among authors: unadkat jd. Cancer Chemother Pharmacol. 2000;45(4):273-8. doi: 10.1007/s002800050040. Cancer Chemother Pharmacol. 2000. PMID: 10755314

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