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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1996 2
1998 2
1999 1
2000 2
2001 3
2002 2
2003 2
2004 3
2005 2
2006 5
2007 5
2008 5
2009 7
2010 4
2011 8
2012 8
2013 7
2014 5
2015 7
2016 9
2017 5
2018 13
2019 10
2020 6
2021 4
2022 6
2023 4
2024 1

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126 results

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Page 1
Insulin sensitization by small molecules enhancing GLUT4 translocation.
Yin TC, Van Vranken JG, Srivastava D, Mittal A, Buscaglia P, Moore AE, Verdinez JA, Graham AE, Walsh SA, Acevedo MA, Kerns RJ, Artemyev NO, Gygi SP, Sebag JA. Yin TC, et al. Cell Chem Biol. 2023 Aug 17;30(8):933-942.e6. doi: 10.1016/j.chembiol.2023.06.012. Epub 2023 Jul 14. Cell Chem Biol. 2023. PMID: 37453421
Using proteomic and CRISPR-based approaches, we identified the targets of those compounds as Unc119 proteins and solved the structure of Unc119 bound to the insulin sensitizer. This study identifies compounds that have the potential to be developed into diabetes tre …
Using proteomic and CRISPR-based approaches, we identified the targets of those compounds as Unc119 proteins and solved the structure …
A Novel Role for UNC119 as an Enhancer of Synaptic Transmission.
Fehlhaber KE, Majumder A, Boyd KK, Griffis KG, Artemyev NO, Fain GL, Sampath AP. Fehlhaber KE, et al. Int J Mol Sci. 2023 Apr 30;24(9):8106. doi: 10.3390/ijms24098106. Int J Mol Sci. 2023. PMID: 37175812 Free PMC article.
Mammalian UNC119 is a ciliary trafficking chaperone highly expressed in the inner segment of retinal photoreceptors. Previous research has shown that UNC119 can bind to transducin, the synaptic ribbon protein RIBEYE, and the calcium-binding protein CaBP4, suggesting …
Mammalian UNC119 is a ciliary trafficking chaperone highly expressed in the inner segment of retinal photoreceptors. Previous researc …
Clinical-genetic findings in a group of subjects with macular dystrophies due to mutations in rare inherited retinopathy genes.
Zenteno JC, Arce-Gonzalez R, Matsui R, Lopez-Bolaños A, Montes L, Martinez-Aguilar A, Chacon-Camacho OF. Zenteno JC, et al. Graefes Arch Clin Exp Ophthalmol. 2023 Feb;261(2):353-365. doi: 10.1007/s00417-022-05786-4. Epub 2022 Aug 10. Graefes Arch Clin Exp Ophthalmol. 2023. PMID: 35947183
Three cases had mutations in genes associated with autosomal dominant inheritance (UNC119 and PRPH2) while the remaining five cases had mutations in genes associated with autosomal recessive inheritance (CNGA3, POC1B, BEST1, CYP2U1, and PROM1). ...
Three cases had mutations in genes associated with autosomal dominant inheritance (UNC119 and PRPH2) while the remaining five cases h …
Ciliary Proteins Repurposed by the Synaptic Ribbon: Trafficking Myristoylated Proteins at Rod Photoreceptor Synapses.
Suiwal S, Dembla M, Schwarz K, Katiyar R, Jung M, Carius Y, Maxeiner S, Lauterbach MA, Lancaster CRD, Schmitz F. Suiwal S, et al. Int J Mol Sci. 2022 Jun 27;23(13):7135. doi: 10.3390/ijms23137135. Int J Mol Sci. 2022. PMID: 35806143 Free PMC article.
The Unc119 protein mediates transport of myristoylated proteins to the photoreceptor outer segment, a specialized primary cilium. ...These findings indicate that the synaptic ribbon could be involved in the discharge of Unc119-bound lipid-modified proteins. In agree …
The Unc119 protein mediates transport of myristoylated proteins to the photoreceptor outer segment, a specialized primary cilium. ... …
126 results