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Comprehensive study on regional human intestinal permeability and prediction of fraction absorbed of drugs using the Ussing chamber technique.
Sjöberg Å, Lutz M, Tannergren C, Wingolf C, Borde A, Ungell AL. Sjöberg Å, et al. Among authors: ungell al. Eur J Pharm Sci. 2013 Jan 23;48(1-2):166-80. doi: 10.1016/j.ejps.2012.10.007. Epub 2012 Oct 26. Eur J Pharm Sci. 2013. PMID: 23103351
Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical Models.
Peters SA, Jones CR, Ungell AL, Hatley OJ. Peters SA, et al. Among authors: ungell al. Clin Pharmacokinet. 2016 Jun;55(6):673-96. doi: 10.1007/s40262-015-0351-6. Clin Pharmacokinet. 2016. PMID: 26895020 Free PMC article. Review.
Gut Wall Metabolism. Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination.
Jones CR, Hatley OJ, Ungell AL, Hilgendorf C, Peters SA, Rostami-Hodjegan A. Jones CR, et al. Among authors: ungell al. AAPS J. 2016 May;18(3):589-604. doi: 10.1208/s12248-016-9889-y. Epub 2016 Mar 10. AAPS J. 2016. PMID: 26964996 Free PMC article. Review.
The Effects of Pregnenolone 16α-Carbonitrile Dosing on Digoxin Pharmacokinetics and Intestinal Absorption in the Rat.
Lowes S, Haslam IS, Fihn BM, Hilgendorf C, Karlsson JE, Simmons NL, Ungell AL. Lowes S, et al. Among authors: ungell al. Pharmaceutics. 2010 Mar 15;2(1):61-77. doi: 10.3390/pharmaceutics2010061. Pharmaceutics. 2010. PMID: 27721343 Free PMC article.
Characterization of THLE-cytochrome P450 (P450) cell lines: gene expression background and relationship to P450-enzyme activity.
Soltanpour Y, Hilgendorf C, Ahlström MM, Foster AJ, Kenna JG, Petersen A, Ungell AL. Soltanpour Y, et al. Among authors: ungell al. Drug Metab Dispos. 2012 Nov;40(11):2054-8. doi: 10.1124/dmd.112.045815. Epub 2012 Jul 30. Drug Metab Dispos. 2012. PMID: 22851615
Impact of input parameters on the prediction of hepatic plasma clearance using the well-stirred model.
Wan H, Bold P, Larsson LO, Ulander J, Peters S, Löfberg B, Ungell AL, Någård M, Llinàs A. Wan H, et al. Among authors: ungell al. Curr Drug Metab. 2010 Sep;11(7):583-94. doi: 10.2174/138920010792927334. Curr Drug Metab. 2010. PMID: 20629632
Physiologically based pharmacokinetic (PBPK) modeling and simulation: applications in lead optimization.
Peters SA, Ungell AL, Dolgos H. Peters SA, et al. Among authors: ungell al. Curr Opin Drug Discov Devel. 2009 Jul;12(4):509-18. Curr Opin Drug Discov Devel. 2009. PMID: 19562647 Review.
Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines.
Hilgendorf C, Ahlin G, Seithel A, Artursson P, Ungell AL, Karlsson J. Hilgendorf C, et al. Among authors: ungell al. Drug Metab Dispos. 2007 Aug;35(8):1333-40. doi: 10.1124/dmd.107.014902. Epub 2007 May 11. Drug Metab Dispos. 2007. PMID: 17496207
Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories.
Hayeshi R, Hilgendorf C, Artursson P, Augustijns P, Brodin B, Dehertogh P, Fisher K, Fossati L, Hovenkamp E, Korjamo T, Masungi C, Maubon N, Mols R, Müllertz A, Mönkkönen J, O'Driscoll C, Oppers-Tiemissen HM, Ragnarsson EG, Rooseboom M, Ungell AL. Hayeshi R, et al. Among authors: ungell al. Eur J Pharm Sci. 2008 Dec 18;35(5):383-96. doi: 10.1016/j.ejps.2008.08.004. Epub 2008 Aug 19. Eur J Pharm Sci. 2008. PMID: 18782614
pH-dependent bidirectional transport of weakly basic drugs across Caco-2 monolayers: implications for drug-drug interactions.
Neuhoff S, Ungell AL, Zamora I, Artursson P. Neuhoff S, et al. Among authors: ungell al. Pharm Res. 2003 Aug;20(8):1141-8. doi: 10.1023/a:1025032511040. Pharm Res. 2003. PMID: 12948010
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