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Inhibition of cytochrome P450 3A4 by extracts and kavalactones of Piper methysticum (Kava-Kava).
Unger M, Holzgrabe U, Jacobsen W, Cummins C, Benet LZ. Unger M, et al. Planta Med. 2002 Dec;68(12):1055-8. doi: 10.1055/s-2002-36360. Planta Med. 2002. PMID: 12494328
Modified nicotine metabolism in transgenic tobacco plants expressing the human cytochrome P450 2A6 cDNA.
Dueckershoff K, Unger M, Frank A, Gillam EM, Guengerich FP, Warzecha H. Dueckershoff K, et al. Among authors: unger m. FEBS Lett. 2005 Apr 25;579(11):2480-4. doi: 10.1016/j.febslet.2005.02.082. FEBS Lett. 2005. PMID: 15848192
Analysis of frankincense from various Boswellia species with inhibitory activity on human drug metabolising cytochrome P450 enzymes using liquid chromatography mass spectrometry after automated on-line extraction.
Frank A, Unger M. Frank A, et al. Among authors: unger m. J Chromatogr A. 2006 Apr 21;1112(1-2):255-62. doi: 10.1016/j.chroma.2005.11.116. Epub 2005 Dec 20. J Chromatogr A. 2006. PMID: 16364338
Random chemistry as a new tool for the generation of small compound libraries: development of a new acetylcholinesterase inhibitor.
Kapková P, Heller E, Unger M, Folkers G, Holzgrabe U. Kapková P, et al. Among authors: unger m. J Med Chem. 2005 Nov 17;48(23):7496-9. doi: 10.1021/jm058041z. J Med Chem. 2005. PMID: 16279811
Capillary zone electrophoresis as a tool for the quality control of goldenseal extracts.
Unger M, Laug S, Holzgrabe U. Unger M, et al. Electrophoresis. 2005 Jun;26(12):2430-6. doi: 10.1002/elps.200410322. Electrophoresis. 2005. PMID: 15912542
Analytical characterisation of crude extracts from an African Ancistrocladus species using high-performance liquid chromatography and capillary electrophoresis coupled to ion trap mass spectrometry.
Unger M, Dreyer M, Specker S, Laug S, Pelzing M, Neusüss C, Holzgrabe U, Bringmann G. Unger M, et al. Phytochem Anal. 2004 Jan-Feb;15(1):21-6. doi: 10.1002/pca.737. Phytochem Anal. 2004. PMID: 14979522
Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction.
Unger M, Frank A. Unger M, et al. Rapid Commun Mass Spectrom. 2004;18(19):2273-81. doi: 10.1002/rcm.1621. Rapid Commun Mass Spectrom. 2004. PMID: 15384148
High-performance liquid chromatographic, capillary electrophoretic and capillary electrophoretic-electrospray ionisation mass spectrometric analysis of selected alkaloid groups.
Stöckigt J, Sheludk Y, Unger M, Gerasimenko I, Warzecha H, Stöckigt D. Stöckigt J, et al. Among authors: unger m. J Chromatogr A. 2002 Aug 16;967(1):85-113. doi: 10.1016/s0021-9673(02)00037-7. J Chromatogr A. 2002. PMID: 12219932 Review.
Extracts and kavalactones of Piper methysticum G. Forst (kava-kava) inhibit P-glycoprotein in vitro.
Weiss J, Sauer A, Frank A, Unger M. Weiss J, et al. Among authors: unger m. Drug Metab Dispos. 2005 Nov;33(11):1580-3. doi: 10.1124/dmd.105.005892. Epub 2005 Jul 28. Drug Metab Dispos. 2005. PMID: 16051732
Pharmacokinetic drug interactions involving Ginkgo biloba.
Unger M. Unger M. Drug Metab Rev. 2013 Aug;45(3):353-85. doi: 10.3109/03602532.2013.815200. Drug Metab Rev. 2013. PMID: 23865865 Review.
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