Unoki T - Search Results

1

Adaptive Responses to Electrophilic Stress and Reactive Sulfur Species as their Regulator Molecules.

Kumagai Y, Akiyama M, Unoki T. Kumagai Y, et al. Among authors: unoki t. Toxicol Res. 2019 Oct;35(4):303-310. doi: 10.5487/TR.2019.35.4.303. Epub 2019 Oct 15. Toxicol Res. 2019. PMID: 31636841 Free PMC article. Review.

2

Methylmercury, an environmental electrophile capable of activation and disruption of the Akt/CREB/Bcl-2 signal transduction pathway in SH-SY5Y cells.

Unoki T, Abiko Y, Toyama T, Uehara T, Tsuboi K, Nishida M, Kaji T, Kumagai Y. Unoki T, et al. Sci Rep. 2016 Jun 30;6:28944. doi: 10.1038/srep28944. Sci Rep. 2016. PMID: 27357941 Free PMC article.

3

1,4-Naphthoquinone activates the HSP90/HSF1 pathway through the S-arylation of HSP90 in A431 cells: Negative regulation of the redox signal transduction pathway by persulfides/polysulfides.

Abiko Y, Sha L, Shinkai Y, Unoki T, Luong NC, Tsuchiya Y, Watanabe Y, Hirose R, Akaike T, Kumagai Y. Abiko Y, et al. Among authors: unoki t. Free Radic Biol Med. 2017 Mar;104:118-128. doi: 10.1016/j.freeradbiomed.2016.12.047. Epub 2016 Dec 31. Free Radic Biol Med. 2017. PMID: 28049024

4

Polysulfide Na₂S₄ regulates the activation of PTEN/Akt/CREB signaling and cytotoxicity mediated by 1,4-naphthoquinone through formation of sulfur adducts.

Abiko Y, Shinkai Y, Unoki T, Hirose R, Uehara T, Kumagai Y. Abiko Y, et al. Among authors: unoki t. Sci Rep. 2017 Jul 6;7(1):4814. doi: 10.1038/s41598-017-04590-z. Sci Rep. 2017. PMID: 28684787 Free PMC article.

5

The Capture of Cadmium by Reactive Polysulfides Attenuates Cadmium-Induced Adaptive Responses and Hepatotoxicity.

Akiyama M, Shinkai Y, Unoki T, Shim I, Ishii I, Kumagai Y. Akiyama M, et al. Among authors: unoki t. Chem Res Toxicol. 2017 Dec 18;30(12):2209-2217. doi: 10.1021/acs.chemrestox.7b00278. Epub 2017 Nov 20. Chem Res Toxicol. 2017. PMID: 29116755

6

Molecular Pathways Associated With Methylmercury-Induced Nrf2 Modulation.

Unoki T, Akiyama M, Kumagai Y, Gonçalves FM, Farina M, da Rocha JBT, Aschner M. Unoki T, et al. Front Genet. 2018 Sep 12;9:373. doi: 10.3389/fgene.2018.00373. eCollection 2018. Front Genet. 2018. PMID: 30271424 Free PMC article. Review.

7

Environmental Electrophile-Mediated Toxicity in Mice Lacking Nrf2, CSE, or Both.

Akiyama M, Unoki T, Shinkai Y, Ishii I, Ida T, Akaike T, Yamamoto M, Kumagai Y. Akiyama M, et al. Among authors: unoki t. Environ Health Perspect. 2019 Jun;127(6):67002. doi: 10.1289/EHP4949. Epub 2019 Jun 5. Environ Health Perspect. 2019. PMID: 31166132 Free PMC article.

8

Nrf2 Activation and Its Coordination with the Protective Defense Systems in Response to Electrophilic Stress.

Unoki T, Akiyama M, Kumagai Y. Unoki T, et al. Int J Mol Sci. 2020 Jan 15;21(2):545. doi: 10.3390/ijms21020545. Int J Mol Sci. 2020. PMID: 31952233 Free PMC article. Review.

9

Repression of mercury accumulation and adverse effects of methylmercury exposure is mediated by cystathionine γ-lyase to produce reactive sulfur species in mouse brain.

Akiyama M, Unoki T, Yoshida E, Ding Y, Yamakawa H, Shinkai Y, Ishii I, Kumagai Y. Akiyama M, et al. Among authors: unoki t. Toxicol Lett. 2020 May 13;330:128-133. doi: 10.1016/j.toxlet.2020.05.007. Online ahead of print. Toxicol Lett. 2020. PMID: 32413476

10

Erratum: Environmental Electrophile-Mediated Toxicity in Mice Lacking Nrf2, CSE, or Both.

Akiyama M, Unoki T, Shinkai Y, Ishii I, Ida T, Akaike T, Yamamoto M, Kumagai Y. Akiyama M, et al. Among authors: unoki t. Environ Health Perspect. 2020 Jun;128(6):69002. doi: 10.1289/EHP7480. Epub 2020 Jun 16. Environ Health Perspect. 2020. PMID: 32543884 Free PMC article. No abstract available.

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