Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

116 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Non-cognitive behaviours in an APP/PS1 transgenic model of Alzheimer's disease.
Pugh PL, Richardson JC, Bate ST, Upton N, Sunter D. Pugh PL, et al. Among authors: upton n. Behav Brain Res. 2007 Mar 12;178(1):18-28. doi: 10.1016/j.bbr.2006.11.044. Epub 2007 Jan 16. Behav Brain Res. 2007. PMID: 17229472
Longitudinal regional brain volume changes quantified in normal aging and Alzheimer's APP x PS1 mice using MRI.
Maheswaran S, Barjat H, Rueckert D, Bate ST, Howlett DR, Tilling L, Smart SC, Pohlmann A, Richardson JC, Hartkens T, Hill DL, Upton N, Hajnal JV, James MF. Maheswaran S, et al. Among authors: upton n. Brain Res. 2009 May 13;1270:19-32. doi: 10.1016/j.brainres.2009.02.045. Epub 2009 Mar 9. Brain Res. 2009. PMID: 19272356
Satiety enhancement by selective orexin-1 receptor antagonist SB-334867: influence of test context and profile comparison with CCK-8S.
Ishii Y, Blundell JE, Halford JC, Upton N, Porter R, Johns A, Rodgers RJ. Ishii Y, et al. Among authors: upton n. Behav Brain Res. 2005 May 7;160(1):11-24. doi: 10.1016/j.bbr.2004.11.011. Epub 2004 Dec 18. Behav Brain Res. 2005. PMID: 15836896
Anorexia and weight loss in male rats 24 h following single dose treatment with orexin-1 receptor antagonist SB-334867.
Ishii Y, Blundell JE, Halford JC, Upton N, Porter R, Johns A, Jeffrey P, Summerfield S, Rodgers RJ. Ishii Y, et al. Among authors: upton n. Behav Brain Res. 2005 Feb 28;157(2):331-41. doi: 10.1016/j.bbr.2004.07.012. Behav Brain Res. 2005. PMID: 15639184
SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models.
Hirst WD, Stean TO, Rogers DC, Sunter D, Pugh P, Moss SF, Bromidge SM, Riley G, Smith DR, Bartlett S, Heidbreder CA, Atkins AR, Lacroix LP, Dawson LA, Foley AG, Regan CM, Upton N. Hirst WD, et al. Among authors: upton n. Eur J Pharmacol. 2006 Dec 28;553(1-3):109-19. doi: 10.1016/j.ejphar.2006.09.049. Epub 2006 Sep 29. Eur J Pharmacol. 2006. PMID: 17069795
SB-399885 (N-[3,5-dichloro-2-(methoxy)phenyl]-4-(methoxy)-3-(1-piperazinyl)benzenesulfonamide) has high affinity for human recombinant and native 5-HT(6) receptors, with pK(i) values 9.11+/-0.03 and 9.02+/-0.05, respectively and is a potent competitive antagonist (pA(2) 7. …
SB-399885 (N-[3,5-dichloro-2-(methoxy)phenyl]-4-(methoxy)-3-(1-piperazinyl)benzenesulfonamide) has high affinity for human recombinan …
Symptomatic treatment of Alzheimer's disease: identification of biomarkers to aid translation from bench to bedside.
Irving EA, Upton N. Irving EA, et al. Among authors: upton n. Biomark Med. 2007 Jun;1(1):93-110. doi: 10.2217/17520363.1.1.93. Biomark Med. 2007. PMID: 20477463
SB-649915-B, a novel 5-HT1A/B autoreceptor antagonist and serotonin reuptake inhibitor, is anxiolytic and displays fast onset activity in the rat high light social interaction test.
Starr KR, Price GW, Watson JM, Atkinson PJ, Arban R, Melotto S, Dawson LA, Hagan JJ, Upton N, Duxon MS. Starr KR, et al. Among authors: upton n. Neuropsychopharmacology. 2007 Oct;32(10):2163-72. doi: 10.1038/sj.npp.1301341. Epub 2007 Mar 14. Neuropsychopharmacology. 2007. PMID: 17356576
A novel behavioural registration system LABORAS and the social interaction paradigm detect long-term functional deficits following middle cerebral artery occlusion in the rat.
Quinn LP, Grundy RI, Campbell CA, Collier S, Lawman A, Stean TO, Billinton A, Parsons AA, Upton N, Duxon MS, Irving EA. Quinn LP, et al. Among authors: upton n. Brain Res. 2005 Jan 7;1031(1):118-24. doi: 10.1016/j.brainres.2004.10.036. Brain Res. 2005. PMID: 15621019
BACE1 (beta-secretase) transgenic and knockout mice: identification of neurochemical deficits and behavioral changes.
Harrison SM, Harper AJ, Hawkins J, Duddy G, Grau E, Pugh PL, Winter PH, Shilliam CS, Hughes ZA, Dawson LA, Gonzalez MI, Upton N, Pangalos MN, Dingwall C. Harrison SM, et al. Among authors: upton n. Mol Cell Neurosci. 2003 Nov;24(3):646-55. doi: 10.1016/s1044-7431(03)00227-6. Mol Cell Neurosci. 2003. PMID: 14664815
A behavioural characterisation of the FVB/N mouse strain.
Pugh PL, Ahmed SF, Smith MI, Upton N, Hunter AJ. Pugh PL, et al. Among authors: upton n. Behav Brain Res. 2004 Dec 6;155(2):283-9. doi: 10.1016/j.bbr.2004.04.021. Behav Brain Res. 2004. PMID: 15364488
Here, the behaviour of two mouse strains used in transgenic models, FVB/N and C57BL6/J, were compared. Studies of circadian wheel activity, cognition and aggression revealed considerable phenotypic differences between strains. These data also indicate that the FVB/N
Here, the behaviour of two mouse strains used in transgenic models, FVB/N and C57BL6/J, were compared. Studies of circadian wheel act …
116 results
Jump to page
Feedback