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A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome.
Lu S, Kanekura K, Hara T, Mahadevan J, Spears LD, Oslowski CM, Martinez R, Yamazaki-Inoue M, Toyoda M, Neilson A, Blanner P, Brown CM, Semenkovich CF, Marshall BA, Hershey T, Umezawa A, Greer PA, Urano F. Lu S, et al. Among authors: urano f. Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):E5292-301. doi: 10.1073/pnas.1421055111. Epub 2014 Nov 24. Proc Natl Acad Sci U S A. 2014. PMID: 25422446 Free PMC article.
Autosomal dominant diabetes arising from a Wolfram syndrome 1 mutation.
Bonnycastle LL, Chines PS, Hara T, Huyghe JR, Swift AJ, Heikinheimo P, Mahadevan J, Peltonen S, Huopio H, Nuutila P, Narisu N, Goldfeder RL, Stitzel ML, Lu S, Boehnke M, Urano F, Collins FS, Laakso M. Bonnycastle LL, et al. Among authors: urano f. Diabetes. 2013 Nov;62(11):3943-50. doi: 10.2337/db13-0571. Epub 2013 Jul 31. Diabetes. 2013. PMID: 23903355 Free PMC article.
Endoplasmic reticulum stress and pancreatic β-cell death.
Fonseca SG, Gromada J, Urano F. Fonseca SG, et al. Among authors: urano f. Trends Endocrinol Metab. 2011 Jul;22(7):266-74. doi: 10.1016/j.tem.2011.02.008. Epub 2011 Mar 31. Trends Endocrinol Metab. 2011. PMID: 21458293 Free PMC article. Review.
Stress hypERactivation in the β-cell.
Fonseca SG, Urano F, Burcin M, Gromada J. Fonseca SG, et al. Among authors: urano f. Islets. 2010 Jan-Feb;2(1):1-9. doi: 10.4161/isl.2.1.10456. Islets. 2010. PMID: 21099287 Review.
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