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Galactose-modified duocarmycin prodrugs as senolytics.
Guerrero A, Guiho R, Herranz N, Uren A, Withers DJ, Martínez-Barbera JP, Tietze LF, Gil J. Guerrero A, et al. Among authors: uren a. Aging Cell. 2020 Apr;19(4):e13133. doi: 10.1111/acel.13133. Epub 2020 Mar 16. Aging Cell. 2020. PMID: 32175667 Free PMC article.
Cardiac glycosides are broad-spectrum senolytics.
Guerrero A, Herranz N, Sun B, Wagner V, Gallage S, Guiho R, Wolter K, Pombo J, Irvine EE, Innes AJ, Birch J, Glegola J, Manshaei S, Heide D, Dharmalingam G, Harbig J, Olona A, Behmoaras J, Dauch D, Uren AG, Zender L, Vernia S, Martínez-Barbera JP, Heikenwalder M, Withers DJ, Gil J. Guerrero A, et al. Among authors: uren ag. Nat Metab. 2019 Nov;1(11):1074-1088. doi: 10.1038/s42255-019-0122-z. Epub 2019 Oct 21. Nat Metab. 2019. PMID: 31799499 Free PMC article.
Visualizing Changes in Cdkn1c Expression Links Early-Life Adversity to Imprint Mis-regulation in Adults.
Van de Pette M, Abbas A, Feytout A, McNamara G, Bruno L, To WK, Dimond A, Sardini A, Webster Z, McGinty J, Paul EJ, Ungless MA, French PMW, Withers DJ, Uren A, Ferguson-Smith AC, Merkenschlager M, John RM, Fisher AG. Van de Pette M, et al. Among authors: uren a. Cell Rep. 2017 Jan 31;18(5):1090-1099. doi: 10.1016/j.celrep.2017.01.010. Cell Rep. 2017. PMID: 28147266 Free PMC article.
Epigenetic changes induced by in utero dietary challenge result in phenotypic variability in successive generations of mice.
Van de Pette M, Dimond A, Galvão AM, Millership SJ, To W, Prodani C, McNamara G, Bruno L, Sardini A, Webster Z, McGinty J, French PMW, Uren AG, Castillo-Fernandez J, Watkinson W, Ferguson-Smith AC, Merkenschlager M, John RM, Kelsey G, Fisher AG. Van de Pette M, et al. Among authors: uren ag. Nat Commun. 2022 May 5;13(1):2464. doi: 10.1038/s41467-022-30022-2. Nat Commun. 2022. PMID: 35513363 Free PMC article.
Subclonal mutation selection in mouse lymphomagenesis identifies known cancer loci and suggests novel candidates.
Webster P, Dawes JC, Dewchand H, Takacs K, Iadarola B, Bolt BJ, Caceres JJ, Kaczor J, Dharmalingam G, Dore M, Game L, Adejumo T, Elliott J, Naresh K, Karimi M, Rekopoulou K, Tan G, Paccanaro A, Uren AG. Webster P, et al. Among authors: uren ag. Nat Commun. 2018 Jul 9;9(1):2649. doi: 10.1038/s41467-018-05069-9. Nat Commun. 2018. PMID: 29985390 Free PMC article.
Author Correction: Subclonal mutation selection in mouse lymphomagenesis identifies known cancer loci and suggests novel candidates.
Webster P, Dawes JC, Dewchand H, Takacs K, Iadarola B, Bolt BJ, Caceres JJ, Kaczor J, Dharmalingam G, Dore M, Game L, Adejumo T, Elliott J, Naresh K, Karimi M, Rekopoulou K, Tan G, Paccanaro A, Uren AG. Webster P, et al. Among authors: uren ag. Nat Commun. 2019 Mar 6;10(1):1167. doi: 10.1038/s41467-019-09109-w. Nat Commun. 2019. PMID: 30842421 Free PMC article.
LUMI-PCR: an Illumina platform ligation-mediated PCR protocol for integration site cloning, provides molecular quantitation of integration sites.
Dawes JC, Webster P, Iadarola B, Garcia-Diaz C, Dore M, Bolt BJ, Dewchand H, Dharmalingam G, McLatchie AP, Kaczor J, Caceres JJ, Paccanaro A, Game L, Parrinello S, Uren AG. Dawes JC, et al. Among authors: uren ag. Mob DNA. 2020 Feb 4;11:7. doi: 10.1186/s13100-020-0201-4. eCollection 2020. Mob DNA. 2020. PMID: 32042315 Free PMC article.
Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells.
Curry E, Green I, Chapman-Rothe N, Shamsaei E, Kandil S, Cherblanc FL, Payne L, Bell E, Ganesh T, Srimongkolpithak N, Caron J, Li F, Uren AG, Snyder JP, Vedadi M, Fuchter MJ, Brown R. Curry E, et al. Clin Epigenetics. 2015 Aug 21;7(1):84. doi: 10.1186/s13148-015-0118-9. eCollection 2015. Clin Epigenetics. 2015. PMID: 26300989 Free PMC article.
222 results